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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2C3
All Species:
27.27
Human Site:
Y86
Identified Species:
50
UniProt:
Q9H9G7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9G7
NP_079128.2
860
97360
Y86
F
G
D
R
R
P
V
Y
D
G
K
R
S
L
Y
Chimpanzee
Pan troglodytes
XP_524664
845
95948
Y71
F
G
D
R
R
P
V
Y
D
G
K
R
S
L
Y
Rhesus Macaque
Macaca mulatta
XP_001100725
1053
117937
Q277
M
V
Q
H
F
K
T
Q
I
F
G
D
R
K
P
Dog
Lupus familis
XP_532562
881
100044
Y102
F
G
D
R
R
P
V
Y
D
G
K
R
S
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8CJF9
860
97222
Y86
F
G
D
R
R
P
V
Y
D
G
K
R
S
L
Y
Rat
Rattus norvegicus
Q9QZ81
860
97300
Q86
M
V
Q
H
F
K
T
Q
I
F
G
D
R
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510243
1052
118200
Y278
F
G
D
R
R
P
V
Y
D
G
K
R
S
L
Y
Chicken
Gallus gallus
Q5ZLG4
860
97253
Y86
F
G
D
R
R
P
V
Y
D
G
K
R
S
L
Y
Frog
Xenopus laevis
Q4KLV6
884
99519
P98
M
V
R
H
F
K
M
P
I
F
G
D
N
Q
P
Zebra Danio
Brachydanio rerio
A3KPK0
860
97313
Y86
F
G
D
R
R
P
V
Y
D
G
K
K
S
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUQ5
1214
136831
Q459
F
E
Q
F
R
V
D
Q
L
G
G
A
V
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34681
1040
115397
H164
A
L
A
Y
D
G
A
H
Q
L
Y
T
V
A
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04379
1048
116172
R244
R
D
S
H
L
G
S
R
L
P
A
Y
D
G
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
62.2
97.1
N.A.
98.7
80.2
N.A.
81.4
99
80.1
95.1
N.A.
22.9
N.A.
32.3
N.A.
Protein Similarity:
100
98.2
71.9
97.3
N.A.
99
89.7
N.A.
81.5
99.1
88.3
97.7
N.A.
36.4
N.A.
50
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
100
100
0
93.3
N.A.
26.6
N.A.
0
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
0
N.A.
100
100
13.3
100
N.A.
26.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
8
0
0
0
8
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
54
0
8
0
8
0
54
0
0
24
8
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
62
0
0
8
24
0
0
0
0
24
0
0
0
0
0
% F
% Gly:
0
54
0
0
0
16
0
0
0
62
31
0
0
8
0
% G
% His:
0
0
0
31
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
24
0
0
0
0
54
8
0
16
0
% K
% Leu:
0
8
0
0
8
0
0
0
16
8
0
0
0
62
0
% L
% Met:
24
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
54
0
8
0
8
0
0
0
0
24
% P
% Gln:
0
0
24
0
0
0
0
24
8
0
0
0
0
8
0
% Q
% Arg:
8
0
8
54
62
0
0
8
0
0
0
47
16
0
16
% R
% Ser:
0
0
8
0
0
0
8
0
0
0
0
0
54
0
0
% S
% Thr:
0
0
0
0
0
0
16
0
0
0
0
8
0
0
0
% T
% Val:
0
24
0
0
0
8
54
0
0
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
54
0
0
8
8
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _