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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS7B
All Species:
29.7
Human Site:
S225
Identified Species:
54.44
UniProt:
Q9H9Q2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Q2
NP_073567.1
264
29622
S225
K
T
L
K
A
T
A
S
S
S
A
Q
E
M
E
Chimpanzee
Pan troglodytes
XP_001145635
308
33966
S225
K
T
L
K
A
T
A
S
S
S
A
Q
E
M
E
Rhesus Macaque
Macaca mulatta
XP_001113929
264
29603
S225
K
T
L
K
A
T
A
S
S
S
A
Q
E
M
E
Dog
Lupus familis
XP_543849
275
30288
A225
K
T
I
K
V
T
T
A
A
A
A
A
A
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BV13
264
29671
S225
K
T
L
K
A
T
A
S
S
S
A
Q
E
M
E
Rat
Rattus norvegicus
NP_001102277
322
35922
S283
K
T
L
K
A
T
A
S
S
S
A
Q
E
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518093
661
70489
R427
V
E
K
R
R
R
A
R
I
N
A
S
L
D
Q
Chicken
Gallus gallus
XP_422740
264
29821
S225
K
T
L
K
A
T
A
S
S
S
A
Q
E
M
E
Frog
Xenopus laevis
NP_001089653
264
29433
S225
K
T
L
K
A
T
A
S
S
S
A
Q
D
T
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4S8
278
31049
S233
K
V
L
K
S
Q
T
S
D
S
D
E
S
M
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785591
270
30197
V226
K
A
I
K
A
S
S
V
A
Q
E
G
D
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JU3
260
29450
D225
K
S
L
S
M
K
G
D
V
D
I
R
G
N
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGS1
417
44522
L254
P
S
S
S
S
S
S
L
P
F
S
W
F
N
N
Conservation
Percent
Protein Identity:
100
85
99.6
56.3
N.A.
98.1
80.1
N.A.
23.6
92
85.2
N.A.
N.A.
41.3
N.A.
N.A.
50.3
Protein Similarity:
100
85.3
100
75.2
N.A.
98.8
81
N.A.
31.9
96.5
93.5
N.A.
N.A.
60.4
N.A.
N.A.
71.4
P-Site Identity:
100
100
100
33.3
N.A.
100
100
N.A.
13.3
100
80
N.A.
N.A.
40
N.A.
N.A.
20
P-Site Similarity:
100
100
100
60
N.A.
100
100
N.A.
33.3
100
93.3
N.A.
N.A.
60
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.3
N.A.
23.9
Protein Similarity:
N.A.
N.A.
N.A.
53
N.A.
39.8
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
62
0
62
8
16
8
70
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
8
8
0
16
8
8
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
8
8
47
8
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
0
0
0
8
0
8
0
0
0
0
% I
% Lys:
85
0
8
77
0
8
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
70
0
0
0
0
8
0
0
0
0
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
54
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
16
8
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
8
0
54
0
0
16
% Q
% Arg:
0
0
0
8
8
8
0
8
0
0
0
8
0
0
0
% R
% Ser:
0
16
8
16
16
16
16
62
54
62
8
8
8
0
8
% S
% Thr:
0
62
0
0
0
62
16
0
0
0
0
0
0
16
0
% T
% Val:
8
8
0
0
8
0
0
8
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _