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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS7B
All Species:
39.39
Human Site:
S254
Identified Species:
72.22
UniProt:
Q9H9Q2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Q2
NP_073567.1
264
29622
S254
R
Q
P
T
K
K
M
S
K
V
K
G
L
V
S
Chimpanzee
Pan troglodytes
XP_001145635
308
33966
S254
R
Q
P
T
K
K
M
S
K
V
K
G
P
S
C
Rhesus Macaque
Macaca mulatta
XP_001113929
264
29603
S254
R
Q
P
T
K
K
M
S
K
V
K
G
L
V
S
Dog
Lupus familis
XP_543849
275
30288
S259
R
Q
P
S
K
K
A
S
K
G
K
G
L
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BV13
264
29671
S254
R
Q
P
T
K
K
M
S
K
V
K
G
L
V
S
Rat
Rattus norvegicus
NP_001102277
322
35922
S312
R
Q
P
T
K
K
M
S
K
V
K
G
L
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518093
661
70489
T636
R
E
W
G
R
P
V
T
R
M
S
T
T
P
R
Chicken
Gallus gallus
XP_422740
264
29821
S254
R
Q
P
T
K
K
M
S
K
V
K
G
L
V
S
Frog
Xenopus laevis
NP_001089653
264
29433
S254
R
Q
P
T
K
K
M
S
K
V
K
G
L
V
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4S8
278
31049
S262
S
E
L
R
K
K
P
S
K
L
R
N
P
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785591
270
30197
S254
M
K
P
S
K
K
P
S
K
M
K
G
L
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JU3
260
29450
P251
Y
E
E
D
G
I
R
P
K
R
R
R
H
P
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SGS1
417
44522
S300
Y
R
S
S
Q
R
G
S
H
Q
Q
H
Q
N
Q
Conservation
Percent
Protein Identity:
100
85
99.6
56.3
N.A.
98.1
80.1
N.A.
23.6
92
85.2
N.A.
N.A.
41.3
N.A.
N.A.
50.3
Protein Similarity:
100
85.3
100
75.2
N.A.
98.8
81
N.A.
31.9
96.5
93.5
N.A.
N.A.
60.4
N.A.
N.A.
71.4
P-Site Identity:
100
80
100
66.6
N.A.
100
100
N.A.
6.6
100
100
N.A.
N.A.
33.3
N.A.
N.A.
53.3
P-Site Similarity:
100
80
100
73.3
N.A.
100
100
N.A.
46.6
100
100
N.A.
N.A.
53.3
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.3
N.A.
23.9
Protein Similarity:
N.A.
N.A.
N.A.
53
N.A.
39.8
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
24
8
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
0
8
0
0
8
0
70
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
8
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
77
77
0
0
85
0
70
0
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
8
0
0
62
0
0
% L
% Met:
8
0
0
0
0
0
54
0
0
16
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
70
0
0
8
16
8
0
0
0
0
16
16
0
% P
% Gln:
0
62
0
0
8
0
0
0
0
8
8
0
8
0
8
% Q
% Arg:
70
8
0
8
8
8
8
0
8
8
16
8
0
24
8
% R
% Ser:
8
0
8
24
0
0
0
85
0
0
8
0
0
8
54
% S
% Thr:
0
0
0
54
0
0
0
8
0
0
0
8
8
0
0
% T
% Val:
0
0
0
0
0
0
8
0
0
54
0
0
0
47
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _