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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NHEJ1 All Species: 8.79
Human Site: T173 Identified Species: 32.22
UniProt: Q9H9Q4 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9Q4 NP_079058.1 299 33337 T173 D Y Q E S G A T L I R D R L K
Chimpanzee Pan troglodytes XP_001160321 299 33384 T173 D Y Q E S G A T L I R D R L K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_853192 346 37978 V220 D Y Q E S G A V L S R D R L K
Cat Felis silvestris
Mouse Mus musculus Q3KNJ2 295 32721 G171 I Q A Y Q E S G A V L S R S R
Rat Rattus norvegicus Q6AYI4 304 33866 V178 A Y Q E S G A V L S R G R L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422052 298 32851 T175 D Y R E S G A T L S R D R L R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NV18 309 34164 V172 D Y Q E N G A V L S R A R L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 N.A. 70.8 N.A. 73.9 75.6 N.A. N.A. 49.1 N.A. 35.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 N.A. 77.1 N.A. 81.9 81.9 N.A. N.A. 61.8 N.A. 54.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 86.6 N.A. 6.6 73.3 N.A. N.A. 80 N.A. 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 86.6 N.A. 26.6 73.3 N.A. N.A. 93.3 N.A. 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 15 0 0 0 86 0 15 0 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 72 0 0 0 0 0 0 0 0 0 0 58 0 0 0 % D
% Glu: 0 0 0 86 0 15 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 86 0 15 0 0 0 15 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 0 0 0 0 0 0 29 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 58 % K
% Leu: 0 0 0 0 0 0 0 0 86 0 15 0 0 86 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 15 72 0 15 0 0 0 0 0 0 0 0 0 15 % Q
% Arg: 0 0 15 0 0 0 0 0 0 0 86 0 100 0 29 % R
% Ser: 0 0 0 0 72 0 15 0 0 58 0 15 0 15 0 % S
% Thr: 0 0 0 0 0 0 0 43 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 43 0 15 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 86 0 15 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _