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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
JMJD4
All Species:
17.27
Human Site:
S278
Identified Species:
29.23
UniProt:
Q9H9V9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9V9
NP_001154937.1
463
52493
S278
N
L
P
Y
D
V
T
S
P
A
L
C
D
T
H
Chimpanzee
Pan troglodytes
XP_001143331
463
52487
S278
N
L
P
Y
D
V
T
S
P
A
L
C
D
T
H
Rhesus Macaque
Macaca mulatta
XP_001086580
463
52468
S278
N
L
P
Y
D
V
T
S
P
A
L
C
D
T
H
Dog
Lupus familis
XP_532414
375
43179
G239
I
N
H
N
W
V
N
G
C
N
L
A
N
M
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFT6
427
49134
S237
N
L
P
Y
D
V
T
S
T
E
L
L
D
T
H
Rat
Rattus norvegicus
Q6AYK2
403
46522
T234
N
Q
Q
D
E
A
I
T
W
F
N
V
I
Y
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZHV5
425
49103
P232
L
P
F
D
V
T
A
P
G
L
Q
D
R
S
V
Frog
Xenopus laevis
Q6GND3
403
46584
W235
Q
Q
D
E
A
I
T
W
F
N
V
I
Y
P
R
Zebra Danio
Brachydanio rerio
Q08BY5
422
49874
L237
P
I
L
Q
D
K
G
L
Y
A
Q
F
E
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ97
425
49151
L246
E
L
K
L
N
D
R
L
G
N
L
P
F
S
I
Honey Bee
Apis mellifera
XP_395655
393
46646
Y237
D
Y
T
R
Y
K
A
Y
D
K
R
V
I
K
Y
Nematode Worm
Caenorhab. elegans
Q9GYI4
400
46600
W240
H
P
D
E
G
I
T
W
F
Q
T
V
Y
K
R
Sea Urchin
Strong. purpuratus
XP_797590
433
50024
S239
N
L
A
Y
D
V
T
S
P
E
I
D
D
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_201113
462
54340
W278
L
N
A
Y
N
L
S
W
V
W
D
L
L
W
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.4
59.6
N.A.
68.9
21.3
N.A.
N.A.
54.4
20.7
48.3
N.A.
31.1
37.1
20.9
42.9
Protein Similarity:
100
99.1
96.5
67.1
N.A.
77.5
37.5
N.A.
N.A.
69.3
37.5
66.3
N.A.
45.1
55.2
37.3
60
P-Site Identity:
100
100
100
13.3
N.A.
80
6.6
N.A.
N.A.
0
6.6
13.3
N.A.
13.3
0
6.6
60
P-Site Similarity:
100
100
100
20
N.A.
80
20
N.A.
N.A.
6.6
20
26.6
N.A.
26.6
13.3
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
8
8
15
0
0
29
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
22
0
0
0
% C
% Asp:
8
0
15
15
43
8
0
0
8
0
8
15
36
0
0
% D
% Glu:
8
0
0
15
8
0
0
0
0
15
0
0
8
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
15
8
0
8
8
0
0
% F
% Gly:
0
0
0
0
8
0
8
8
15
0
0
0
0
0
0
% G
% His:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
29
% H
% Ile:
8
8
0
0
0
15
8
0
0
0
8
8
15
0
8
% I
% Lys:
0
0
8
0
0
15
0
0
0
8
0
0
0
15
8
% K
% Leu:
15
43
8
8
0
8
0
15
0
8
43
15
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
43
15
0
8
15
0
8
0
0
22
8
0
8
0
0
% N
% Pro:
8
15
29
0
0
0
0
8
29
0
0
8
0
8
8
% P
% Gln:
8
15
8
8
0
0
0
0
0
8
15
0
0
0
0
% Q
% Arg:
0
0
0
8
0
0
8
0
0
0
8
0
8
0
15
% R
% Ser:
0
0
0
0
0
0
8
36
0
0
0
0
0
15
0
% S
% Thr:
0
0
8
0
0
8
50
8
8
0
8
0
0
29
8
% T
% Val:
0
0
0
0
8
43
0
0
8
0
8
22
0
0
8
% V
% Trp:
0
0
0
0
8
0
0
22
8
8
0
0
0
8
8
% W
% Tyr:
0
8
0
43
8
0
0
8
8
0
0
0
15
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _