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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPF1 All Species: 8.79
Human Site: S10 Identified Species: 12.89
UniProt: Q9H9Y2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9Y2 NP_079341.2 349 40111 S10 K A G D K S S S S G K K S L K
Chimpanzee Pan troglodytes XP_001138063 294 33392
Rhesus Macaque Macaca mulatta XP_001106662 349 40267 S10 K A G E K S S S S W K K S L K
Dog Lupus familis XP_537096 349 40030 G10 K A G G K S G G G G K K G L K
Cat Felis silvestris
Mouse Mus musculus Q7TND5 349 40018 G10 K A G E K S V G G G K R G L K
Rat Rattus norvegicus Q5RJS9 345 39363 G10 K A G E K S G G G G K R G L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520910 227 26648
Chicken Gallus gallus XP_422376 371 42419 R22 P S A L P A E R R G R G A A Q
Frog Xenopus laevis Q8AVP1 343 40190 K10 E K K G P E A K K Q K K M K N
Zebra Danio Brachydanio rerio Q6IQU6 330 38740 D12 K A P V E E M D Q A E C E V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKB4 394 45981 S48 S S D E E A A S S S K K T A K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54073 384 45173 K51 S D E D E P P K K K K K V V K
Sea Urchin Strong. purpuratus XP_001177309 253 29706
Poplar Tree Populus trichocarpa XP_002320911 370 43512 S10 I K R K K S E S E A M E D Y D
Maize Zea mays NP_001141844 360 41511 R28 E G E G R S G R K G K K A R K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38805 295 35103
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.2 97.9 94.5 N.A. 95.1 90.5 N.A. 60.7 76 76.2 71 N.A. 39.5 N.A. 44.7 50.4
Protein Similarity: 100 84.2 99.4 96.8 N.A. 97.1 93.1 N.A. 63.6 83.8 86.2 84.5 N.A. 57.3 N.A. 61.4 60.7
P-Site Identity: 100 0 86.6 66.6 N.A. 60 60 N.A. 0 6.6 13.3 20 N.A. 33.3 N.A. 26.6 0
P-Site Similarity: 100 0 93.3 66.6 N.A. 73.3 73.3 N.A. 0 40 26.6 40 N.A. 73.3 N.A. 40 0
Percent
Protein Identity: 44.5 46.6 N.A. N.A. 42.1 N.A.
Protein Similarity: 58.9 61.1 N.A. N.A. 56.7 N.A.
P-Site Identity: 20 33.3 N.A. N.A. 0 N.A.
P-Site Similarity: 26.6 53.3 N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 38 7 0 0 13 13 0 0 13 0 0 13 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 7 7 13 0 0 0 7 0 0 0 0 7 0 7 % D
% Glu: 13 0 13 25 19 13 13 0 7 0 7 7 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 32 19 0 0 19 19 19 38 0 7 19 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 38 13 7 7 38 0 0 13 19 7 57 44 0 7 57 % K
% Leu: 0 0 0 7 0 0 0 0 0 0 0 0 0 32 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 7 0 7 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 7 0 7 0 13 7 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 7 % Q
% Arg: 0 0 7 0 7 0 0 13 7 0 7 13 0 7 0 % R
% Ser: 13 13 0 0 0 44 13 25 19 7 0 0 13 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % T
% Val: 0 0 0 7 0 0 7 0 0 0 0 0 7 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _