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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPF1 All Species: 29.7
Human Site: S225 Identified Species: 43.56
UniProt: Q9H9Y2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9Y2 NP_079341.2 349 40111 S225 T A H F K M S S V R L R K E I
Chimpanzee Pan troglodytes XP_001138063 294 33392 H171 S T V I P N S H V Y Y R R G L
Rhesus Macaque Macaca mulatta XP_001106662 349 40267 S225 T A H F K M S S V R L R K E I
Dog Lupus familis XP_537096 349 40030 S225 T A H F K M S S V R L R K E I
Cat Felis silvestris
Mouse Mus musculus Q7TND5 349 40018 S225 T A H F K M S S V R L R K E I
Rat Rattus norvegicus Q5RJS9 345 39363 K222 N G P T A H F K M S S V R L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520910 227 26648 V104 A H F R M S S V R L R K E I K
Chicken Gallus gallus XP_422376 371 42419 S247 T A H F R M S S V R L R K E I
Frog Xenopus laevis Q8AVP1 343 40190 N219 T A H F K I S N V R L R K E M
Zebra Danio Brachydanio rerio Q6IQU6 330 38740 S206 T A H F K V S S V R L R K E M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKB4 394 45981 N268 T A H F K L S N V K L T S D I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54073 384 45173 S260 T A Y F K I N S L T F T Q D L
Sea Urchin Strong. purpuratus XP_001177309 253 29706 N130 T C H Y K M S N V K L R Q D I
Poplar Tree Populus trichocarpa XP_002320911 370 43512 S223 P T A H F K L S R L V L R K D
Maize Zea mays NP_001141844 360 41511 S216 P T A H F K L S K L V L R K D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38805 295 35103 Y172 L P E G P T F Y F K L S S F V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.2 97.9 94.5 N.A. 95.1 90.5 N.A. 60.7 76 76.2 71 N.A. 39.5 N.A. 44.7 50.4
Protein Similarity: 100 84.2 99.4 96.8 N.A. 97.1 93.1 N.A. 63.6 83.8 86.2 84.5 N.A. 57.3 N.A. 61.4 60.7
P-Site Identity: 100 20 100 100 N.A. 100 0 N.A. 6.6 93.3 80 86.6 N.A. 60 N.A. 33.3 60
P-Site Similarity: 100 40 100 100 N.A. 100 13.3 N.A. 20 100 100 100 N.A. 86.6 N.A. 80 93.3
Percent
Protein Identity: 44.5 46.6 N.A. N.A. 42.1 N.A.
Protein Similarity: 58.9 61.1 N.A. N.A. 56.7 N.A.
P-Site Identity: 6.6 6.6 N.A. N.A. 6.6 N.A.
P-Site Similarity: 26.6 26.6 N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 57 13 0 7 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 13 % D
% Glu: 0 0 7 0 0 0 0 0 0 0 0 0 7 44 0 % E
% Phe: 0 0 7 57 13 0 13 0 7 0 7 0 0 7 0 % F
% Gly: 0 7 0 7 0 0 0 0 0 0 0 0 0 7 0 % G
% His: 0 7 57 13 0 7 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 13 0 0 0 0 0 0 0 7 44 % I
% Lys: 0 0 0 0 57 13 0 7 7 19 0 7 44 13 7 % K
% Leu: 7 0 0 0 0 7 13 0 7 19 63 13 0 7 13 % L
% Met: 0 0 0 0 7 38 0 0 7 0 0 0 0 0 13 % M
% Asn: 7 0 0 0 0 7 7 19 0 0 0 0 0 0 0 % N
% Pro: 13 7 7 0 13 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % Q
% Arg: 0 0 0 7 7 0 0 0 13 44 7 57 25 0 7 % R
% Ser: 7 0 0 0 0 7 69 57 0 7 7 7 13 0 0 % S
% Thr: 63 19 0 7 0 7 0 0 0 7 0 13 0 0 0 % T
% Val: 0 0 7 0 0 7 0 7 63 0 13 7 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 7 0 0 0 7 0 7 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _