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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPF1 All Species: 30
Human Site: S265 Identified Species: 44
UniProt: Q9H9Y2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9Y2 NP_079341.2 349 40111 S265 S I G R M F A S L F P H N P Q
Chimpanzee Pan troglodytes XP_001138063 294 33392 S211 T P N G L I L S H L P N G P T
Rhesus Macaque Macaca mulatta XP_001106662 349 40267 S265 S I G R M F A S L F P H N P Q
Dog Lupus familis XP_537096 349 40030 S265 S I G R M F A S L F P H N P Q
Cat Felis silvestris
Mouse Mus musculus Q7TND5 349 40018 S265 S I G R M F A S L F P H N P Q
Rat Rattus norvegicus Q5RJS9 345 39363 M262 L G H S I G R M F A S L F P H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520910 227 26648 L144 I G R M L A S L F P H D P Q F
Chicken Gallus gallus XP_422376 371 42419 S287 S I G R M F A S L F P H D P Q
Frog Xenopus laevis Q8AVP1 343 40190 S259 S I G R M F A S L Y P H D P H
Zebra Danio Brachydanio rerio Q6IQU6 330 38740 A246 S I G R L F A A L F P H D P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKB4 394 45981 A308 T V G R M L G A L F H H D P E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54073 384 45173 L300 I A R M L A C L F P H D P K F
Sea Urchin Strong. purpuratus XP_001177309 253 29706 L170 I G R Q I A A L F P H D P N F
Poplar Tree Populus trichocarpa XP_002320911 370 43512 S263 R I G R L I Q S L F P Q E P N
Maize Zea mays NP_001141844 360 41511 S256 R V G R M I Q S L F P Q D P N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38805 295 35103 R212 R L G Q T V G R L F Q S I L P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.2 97.9 94.5 N.A. 95.1 90.5 N.A. 60.7 76 76.2 71 N.A. 39.5 N.A. 44.7 50.4
Protein Similarity: 100 84.2 99.4 96.8 N.A. 97.1 93.1 N.A. 63.6 83.8 86.2 84.5 N.A. 57.3 N.A. 61.4 60.7
P-Site Identity: 100 20 100 100 N.A. 100 6.6 N.A. 0 93.3 80 80 N.A. 46.6 N.A. 0 6.6
P-Site Similarity: 100 40 100 100 N.A. 100 13.3 N.A. 13.3 100 93.3 100 N.A. 80 N.A. 6.6 20
Percent
Protein Identity: 44.5 46.6 N.A. N.A. 42.1 N.A.
Protein Similarity: 58.9 61.1 N.A. N.A. 56.7 N.A.
P-Site Identity: 53.3 53.3 N.A. N.A. 20 N.A.
P-Site Similarity: 60 66.6 N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 19 50 13 0 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 19 32 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % E
% Phe: 0 0 0 0 0 44 0 0 25 63 0 0 7 0 19 % F
% Gly: 0 19 69 7 0 7 13 0 0 0 0 0 7 0 0 % G
% His: 0 0 7 0 0 0 0 0 7 0 25 50 0 0 13 % H
% Ile: 19 50 0 0 13 19 0 0 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % K
% Leu: 7 7 0 0 32 7 7 19 69 7 0 7 0 7 0 % L
% Met: 0 0 0 13 50 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 0 0 7 25 7 13 % N
% Pro: 0 7 0 0 0 0 0 0 0 19 63 0 19 75 7 % P
% Gln: 0 0 0 13 0 0 13 0 0 0 7 13 0 7 38 % Q
% Arg: 19 0 19 63 0 0 7 7 0 0 0 0 0 0 0 % R
% Ser: 44 0 0 7 0 0 7 57 0 0 7 7 0 0 0 % S
% Thr: 13 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % T
% Val: 0 13 0 0 0 7 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _