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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPF1 All Species: 29.22
Human Site: S343 Identified Species: 42.86
UniProt: Q9H9Y2 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9Y2 NP_079341.2 349 40111 S343 K P R E M D T S R R K F H L _
Chimpanzee Pan troglodytes XP_001138063 294 33392
Rhesus Macaque Macaca mulatta XP_001106662 349 40267 S343 K P R E M D T S R R K F H L _
Dog Lupus familis XP_537096 349 40030 S343 K P R E M D T S R R K F H L _
Cat Felis silvestris
Mouse Mus musculus Q7TND5 349 40018 S343 K P R E M D T S R R K F H L _
Rat Rattus norvegicus Q5RJS9 345 39363
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520910 227 26648
Chicken Gallus gallus XP_422376 371 42419 S365 K R R E M D T S R R K F H L _
Frog Xenopus laevis Q8AVP1 343 40190 S337 K R H E M D T S R R K F H L _
Zebra Danio Brachydanio rerio Q6IQU6 330 38740 S324 K R H E M D S S R R K F H L _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKB4 394 45981 M386 I S N K R H A M E S R R R F F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54073 384 45173 S378 K R H E M E T S R R R F F L _
Sea Urchin Strong. purpuratus XP_001177309 253 29706
Poplar Tree Populus trichocarpa XP_002320911 370 43512 L341 F T L K L R S L Q H E T F D T
Maize Zea mays NP_001141844 360 41511 G334 K L L T L Q H G T F D T R S G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38805 295 35103
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.2 97.9 94.5 N.A. 95.1 90.5 N.A. 60.7 76 76.2 71 N.A. 39.5 N.A. 44.7 50.4
Protein Similarity: 100 84.2 99.4 96.8 N.A. 97.1 93.1 N.A. 63.6 83.8 86.2 84.5 N.A. 57.3 N.A. 61.4 60.7
P-Site Identity: 100 0 100 100 N.A. 100 0 N.A. 0 92.8 85.7 78.5 N.A. 0 N.A. 64.2 0
P-Site Similarity: 100 0 100 100 N.A. 100 0 N.A. 0 92.8 85.7 85.7 N.A. 13.3 N.A. 78.5 0
Percent
Protein Identity: 44.5 46.6 N.A. N.A. 42.1 N.A.
Protein Similarity: 58.9 61.1 N.A. N.A. 56.7 N.A.
P-Site Identity: 0 6.6 N.A. N.A. 0 N.A.
P-Site Similarity: 33.3 20 N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 44 0 0 0 0 7 0 0 7 0 % D
% Glu: 0 0 0 50 0 7 0 0 7 0 7 0 0 0 0 % E
% Phe: 7 0 0 0 0 0 0 0 0 7 0 50 13 7 7 % F
% Gly: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 7 % G
% His: 0 0 19 0 0 7 7 0 0 7 0 0 44 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 57 0 0 13 0 0 0 0 0 0 44 0 0 0 0 % K
% Leu: 0 7 13 0 13 0 0 7 0 0 0 0 0 50 0 % L
% Met: 0 0 0 0 50 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % Q
% Arg: 0 25 32 0 7 7 0 0 50 50 13 7 13 0 0 % R
% Ser: 0 7 0 0 0 0 13 50 0 7 0 0 0 7 0 % S
% Thr: 0 7 0 7 0 0 44 0 7 0 0 13 0 0 7 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % _