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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPF1 All Species: 34.24
Human Site: Y173 Identified Species: 50.22
UniProt: Q9H9Y2 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H9Y2 NP_079341.2 349 40111 Y173 V I P N S H V Y Y R R G L A L
Chimpanzee Pan troglodytes XP_001138063 294 33392 V123 V D P N D E E V A Y D E A T D
Rhesus Macaque Macaca mulatta XP_001106662 349 40267 Y173 V I P N S H V Y Y R R G L A L
Dog Lupus familis XP_537096 349 40030 Y173 V I P N S H V Y Y R R G L A L
Cat Felis silvestris
Mouse Mus musculus Q7TND5 349 40018 Y173 V I P D S H V Y Y R R G L A L
Rat Rattus norvegicus Q5RJS9 345 39363 Y173 V I P D S H V Y Y R R G L A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520910 227 26648 L56 H V Y Y R R G L A L K K I I P
Chicken Gallus gallus XP_422376 371 42419 Y195 V I P N S H V Y Y R R G L A L
Frog Xenopus laevis Q8AVP1 343 40190 Y167 I I P N S D V Y Y R R G L A L
Zebra Danio Brachydanio rerio Q6IQU6 330 38740 Y154 V I P H A Y V Y Y R R G L A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKB4 394 45981 K216 I F P N A L V K I R N K S S V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P54073 384 45173 F208 C I P N S E I F T R K N V L L
Sea Urchin Strong. purpuratus XP_001177309 253 29706 H82 S E V H H R R H L P L K R I I
Poplar Tree Populus trichocarpa XP_002320911 370 43512 Y172 V I P N A H Y Y K R G T Y D L
Maize Zea mays NP_001141844 360 41511 V165 V I P N S Q Y V K R G T Y E L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38805 295 35103 V124 I L P N V T F V K R K F G Y K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.2 97.9 94.5 N.A. 95.1 90.5 N.A. 60.7 76 76.2 71 N.A. 39.5 N.A. 44.7 50.4
Protein Similarity: 100 84.2 99.4 96.8 N.A. 97.1 93.1 N.A. 63.6 83.8 86.2 84.5 N.A. 57.3 N.A. 61.4 60.7
P-Site Identity: 100 20 100 100 N.A. 93.3 93.3 N.A. 0 100 86.6 80 N.A. 26.6 N.A. 40 0
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 20 100 93.3 100 N.A. 53.3 N.A. 66.6 20
Percent
Protein Identity: 44.5 46.6 N.A. N.A. 42.1 N.A.
Protein Similarity: 58.9 61.1 N.A. N.A. 56.7 N.A.
P-Site Identity: 53.3 46.6 N.A. N.A. 20 N.A.
P-Site Similarity: 60 46.6 N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 0 0 0 13 0 0 0 7 50 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 13 7 7 0 0 0 0 7 0 0 7 7 % D
% Glu: 0 7 0 0 0 13 7 0 0 0 0 7 0 7 0 % E
% Phe: 0 7 0 0 0 0 7 7 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 0 13 50 7 0 0 % G
% His: 7 0 0 13 7 44 0 7 0 0 0 0 0 0 0 % H
% Ile: 19 69 0 0 0 0 7 0 7 0 0 0 7 13 7 % I
% Lys: 0 0 0 0 0 0 0 7 19 0 19 19 0 0 7 % K
% Leu: 0 7 0 0 0 7 0 7 7 7 7 0 50 7 69 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 69 0 0 0 0 0 0 7 7 0 0 0 % N
% Pro: 0 0 88 0 0 0 0 0 0 7 0 0 0 0 7 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 7 13 7 0 0 82 50 0 7 0 0 % R
% Ser: 7 0 0 0 57 0 0 0 0 0 0 0 7 7 0 % S
% Thr: 0 0 0 0 0 7 0 0 7 0 0 13 0 7 0 % T
% Val: 63 7 7 0 7 0 57 19 0 0 0 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 7 0 7 13 57 50 7 0 0 13 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _