KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPN2
All Species:
25.76
Human Site:
Y295
Identified Species:
47.22
UniProt:
Q9H9Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y4
NP_060536.3
310
34561
Y295
T
L
G
I
Q
E
K
Y
L
A
P
S
N
Q
S
Chimpanzee
Pan troglodytes
XP_001146839
320
35455
Y305
T
L
G
I
Q
E
K
Y
L
A
P
S
N
Q
S
Rhesus Macaque
Macaca mulatta
XP_001110243
310
34443
Y295
T
L
G
I
Q
E
K
Y
L
A
P
S
N
Q
S
Dog
Lupus familis
XP_852536
310
34495
Y295
T
L
G
I
Q
E
K
Y
L
A
P
P
D
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEJ1
310
34537
Y295
T
L
G
I
Q
E
K
Y
L
A
P
S
E
Q
T
Rat
Rattus norvegicus
Q6R518
284
32784
E269
E
P
K
E
H
E
E
E
S
S
S
M
F
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66KF6
318
35327
V304
L
A
F
Q
E
K
Y
V
E
N
D
G
R
T
V
Zebra Danio
Brachydanio rerio
Q6PUR6
311
35074
Y296
T
L
G
V
Q
E
K
Y
L
D
A
T
K
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46577
355
39639
N317
G
K
A
V
H
D
L
N
K
V
A
N
P
D
E
Sea Urchin
Strong. purpuratus
XP_794415
308
34563
Y288
T
A
S
V
Q
E
K
Y
M
Q
E
D
S
K
P
Poplar Tree
Populus trichocarpa
XP_002320027
301
33881
D277
K
I
A
V
R
P
V
D
W
D
Y
Y
R
V
A
Maize
Zea mays
NP_001131405
304
34457
Y290
T
A
E
V
Q
E
K
Y
M
K
D
D
E
F
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08726
347
39706
R292
A
N
Y
D
I
Q
D
R
W
I
D
N
K
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
99.6
97.7
N.A.
95.4
37.4
N.A.
N.A.
N.A.
63.2
71
N.A.
N.A.
N.A.
22.5
61.2
Protein Similarity:
100
96.5
99.6
99
N.A.
97.7
55.8
N.A.
N.A.
N.A.
76.7
84.2
N.A.
N.A.
N.A.
43.6
77.4
P-Site Identity:
100
100
100
86.6
N.A.
86.6
6.6
N.A.
N.A.
N.A.
0
53.3
N.A.
N.A.
N.A.
0
33.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
N.A.
N.A.
13.3
66.6
N.A.
N.A.
N.A.
20
60
Percent
Protein Identity:
52.9
53.8
N.A.
N.A.
41.2
N.A.
Protein Similarity:
71.9
71.2
N.A.
N.A.
60.5
N.A.
P-Site Identity:
0
33.3
N.A.
N.A.
0
N.A.
P-Site Similarity:
26.6
53.3
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
16
0
0
0
0
0
0
39
16
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
8
8
0
16
24
16
8
16
0
% D
% Glu:
8
0
8
8
8
70
8
8
8
0
8
0
16
8
16
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
8
8
0
% F
% Gly:
8
0
47
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
39
8
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
8
8
8
0
0
8
62
0
8
8
0
0
16
8
8
% K
% Leu:
8
47
0
0
0
0
8
0
47
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
16
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
8
0
16
24
8
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
0
39
8
8
0
8
% P
% Gln:
0
0
0
8
62
8
0
0
0
8
0
0
0
39
0
% Q
% Arg:
0
0
0
0
8
0
0
8
0
0
0
0
16
0
0
% R
% Ser:
0
0
8
0
0
0
0
0
8
8
8
31
8
0
31
% S
% Thr:
62
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% T
% Val:
0
0
0
39
0
0
8
8
0
8
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
62
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _