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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
17.88
Human Site:
S12
Identified Species:
28.1
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
S12
S
R
W
R
N
L
P
S
G
P
S
L
K
H
L
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
S12
S
R
W
R
N
L
P
S
G
P
S
L
K
H
L
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
S12
S
R
W
R
N
L
P
S
G
P
T
L
K
H
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
S12
G
R
W
R
N
L
P
S
G
P
S
L
K
H
L
Rat
Rattus norvegicus
O54888
1135
127691
S12
S
R
W
R
N
L
P
S
G
P
S
L
K
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
G23
W
D
S
N
D
N
H
G
I
R
Y
A
L
H
V
Chicken
Gallus gallus
XP_415007
1041
117633
H12
E
T
R
A
P
R
G
H
G
Y
G
G
D
T
S
Frog
Xenopus laevis
NP_001080005
1134
128197
R12
A
K
W
Q
A
L
L
R
E
P
S
L
A
K
L
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
L18
T
E
P
S
L
K
H
L
T
E
A
G
F
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
F21
L
T
N
S
R
P
E
F
K
Q
I
P
K
K
L
Honey Bee
Apis mellifera
XP_001120416
1121
127333
F14
L
T
N
T
S
K
N
F
G
K
P
P
E
K
Q
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
A39
A
C
W
V
V
I
S
A
Y
F
D
E
K
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
D17
P
Q
Y
V
E
D
D
D
D
E
E
I
T
Q
E
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
D15
P
G
Q
A
R
T
A
D
F
R
T
L
E
R
E
Red Bread Mold
Neurospora crassa
O74633
1234
138583
L39
D
R
T
A
Y
P
A
L
Q
A
A
V
D
P
H
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
93.3
100
N.A.
6.6
6.6
40
0
N.A.
13.3
6.6
20
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
100
N.A.
20
6.6
60
20
N.A.
13.3
20
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
20
7
0
14
7
0
7
14
7
7
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
7
7
7
14
7
0
7
0
14
0
0
% D
% Glu:
7
7
0
0
7
0
7
0
7
14
7
7
14
0
14
% E
% Phe:
0
0
0
0
0
0
0
14
7
7
0
0
7
0
0
% F
% Gly:
7
7
0
0
0
0
7
7
47
0
7
14
0
14
0
% G
% His:
0
0
0
0
0
0
14
7
0
0
0
0
0
40
7
% H
% Ile:
0
0
0
0
0
7
0
0
7
0
7
7
0
0
0
% I
% Lys:
0
7
0
0
0
14
0
0
7
7
0
0
47
20
0
% K
% Leu:
14
0
0
0
7
40
7
14
0
0
0
47
7
0
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
14
7
34
7
7
0
0
0
0
0
0
0
0
% N
% Pro:
14
0
7
0
7
14
34
0
0
40
7
14
0
7
0
% P
% Gln:
0
7
7
7
0
0
0
0
7
7
0
0
0
7
7
% Q
% Arg:
0
40
7
34
14
7
0
7
0
14
0
0
0
7
0
% R
% Ser:
27
0
7
14
7
0
7
34
0
0
34
0
0
0
7
% S
% Thr:
7
20
7
7
0
7
0
0
7
0
14
0
7
7
0
% T
% Val:
0
0
0
14
7
0
0
0
0
0
0
7
0
0
14
% V
% Trp:
7
0
47
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
7
0
0
0
7
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _