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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
4.55
Human Site:
S408
Identified Species:
7.14
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
S408
D
K
K
A
Q
K
T
S
V
S
M
N
T
D
N
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
S408
D
K
K
A
Q
K
T
S
V
S
M
N
T
D
N
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
N408
D
K
K
A
Q
K
T
N
V
S
M
N
T
D
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
N408
D
K
R
A
Q
K
A
N
V
S
I
N
N
E
N
Rat
Rattus norvegicus
O54888
1135
127691
N408
D
K
R
A
Q
K
T
N
V
S
I
N
N
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
N419
D
K
R
A
Q
K
T
N
I
S
L
N
S
E
N
Chicken
Gallus gallus
XP_415007
1041
117633
G358
L
G
M
L
Q
D
S
G
L
C
V
V
G
D
K
Frog
Xenopus laevis
NP_001080005
1134
128197
L407
L
D
K
R
A
H
K
L
V
D
L
T
T
E
T
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
V406
L
E
K
K
P
Q
R
V
G
G
L
T
P
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
D408
Q
K
K
L
T
S
P
D
A
L
V
T
S
A
V
Honey Bee
Apis mellifera
XP_001120416
1121
127333
N402
K
R
A
R
S
A
G
N
R
Y
T
L
N
V
Q
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
K427
E
M
R
M
T
A
Q
K
Y
I
N
K
N
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
Q425
R
D
V
R
S
Y
V
Q
K
C
V
D
N
G
K
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
N439
I
N
R
G
M
A
I
N
F
K
D
K
R
Y
M
Red Bread Mold
Neurospora crassa
O74633
1234
138583
D445
P
T
V
S
F
Q
S
D
T
F
L
K
D
F
P
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
60
66.6
N.A.
60
13.3
20
13.3
N.A.
13.3
0
6.6
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
93.3
N.A.
100
33.3
33.3
40
N.A.
26.6
13.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
0
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
40
7
20
7
0
7
0
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% C
% Asp:
40
14
0
0
0
7
0
14
0
7
7
7
7
40
7
% D
% Glu:
7
7
0
0
0
0
0
0
0
0
0
0
0
27
0
% E
% Phe:
0
0
0
0
7
0
0
0
7
7
0
0
0
7
0
% F
% Gly:
0
7
0
7
0
0
7
7
7
7
0
0
7
7
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
7
7
14
0
0
0
0
% I
% Lys:
7
47
40
7
0
40
7
7
7
7
0
20
0
0
14
% K
% Leu:
20
0
0
14
0
0
0
7
7
7
27
7
0
0
0
% L
% Met:
0
7
7
7
7
0
0
0
0
0
20
0
0
0
7
% M
% Asn:
0
7
0
0
0
0
0
40
0
0
7
40
34
0
40
% N
% Pro:
7
0
0
0
7
0
7
0
0
0
0
0
7
0
7
% P
% Gln:
7
0
0
0
47
14
7
7
0
0
0
0
0
0
7
% Q
% Arg:
7
7
34
20
0
0
7
0
7
0
0
0
7
0
0
% R
% Ser:
0
0
0
7
14
7
14
14
0
40
0
0
14
0
7
% S
% Thr:
0
7
0
0
14
0
34
0
7
0
7
20
27
0
7
% T
% Val:
0
0
14
0
0
0
7
7
40
0
20
7
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
7
7
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _