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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
28.79
Human Site:
T1109
Identified Species:
45.24
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
T1109
S
R
S
D
T
I
D
T
V
S
V
P
Y
V
F
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
T1109
N
R
S
D
T
I
D
T
V
S
V
P
Y
V
F
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
T1109
N
R
S
D
T
I
D
T
V
S
V
P
Y
V
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
T1109
G
R
S
D
T
I
D
T
V
S
V
P
Y
V
F
Rat
Rattus norvegicus
O54888
1135
127691
T1109
G
R
S
D
S
I
D
T
V
S
V
P
Y
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
T1120
R
Q
S
D
T
I
E
T
V
S
V
P
Y
V
F
Chicken
Gallus gallus
XP_415007
1041
117633
I1015
R
M
D
T
I
Q
I
I
P
V
P
H
V
F
R
Frog
Xenopus laevis
NP_001080005
1134
128197
A1108
N
R
T
D
T
V
E
A
V
S
V
P
Y
V
F
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
T1106
N
K
S
D
S
I
E
T
V
S
V
P
Y
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
S1100
C
G
D
N
S
S
V
S
M
I
E
I
P
F
S
Honey Bee
Apis mellifera
XP_001120416
1121
127333
D1095
N
E
S
V
R
E
I
D
I
P
Y
I
F
R
Y
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
L1164
I
P
Y
A
C
K
L
L
F
Q
E
L
M
S
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
L1163
I
P
Y
A
C
K
L
L
F
Q
E
L
M
S
M
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
T1143
E
D
A
K
K
L
L
T
K
S
E
D
G
E
K
Red Bread Mold
Neurospora crassa
O74633
1234
138583
E1158
A
V
R
L
D
D
M
E
D
V
D
L
M
Q
I
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
93.3
93.3
N.A.
N.A.
93.3
86.6
N.A.
80
0
66.6
73.3
N.A.
0
6.6
0
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
0
93.3
100
N.A.
26.6
33.3
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
0
26.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
14
0
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
7
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
14
54
7
7
34
7
7
0
7
7
0
0
0
% D
% Glu:
7
7
0
0
0
7
20
7
0
0
27
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
14
0
0
0
7
14
54
% F
% Gly:
14
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
14
0
0
0
7
47
14
7
7
7
0
14
0
0
7
% I
% Lys:
0
7
0
7
7
14
0
0
7
0
0
0
0
0
7
% K
% Leu:
0
0
0
7
0
7
20
14
0
0
0
20
0
0
0
% L
% Met:
0
7
0
0
0
0
7
0
7
0
0
0
20
0
14
% M
% Asn:
34
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
14
0
0
0
0
0
0
7
7
7
54
7
0
0
% P
% Gln:
0
7
0
0
0
7
0
0
0
14
0
0
0
7
0
% Q
% Arg:
14
40
7
0
7
0
0
0
0
0
0
0
0
7
7
% R
% Ser:
7
0
54
0
20
7
0
7
0
60
0
0
0
14
7
% S
% Thr:
0
0
7
7
40
0
0
54
0
0
0
0
0
0
0
% T
% Val:
0
7
0
7
0
7
7
0
54
14
54
0
7
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
0
0
0
0
0
0
0
7
0
54
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _