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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
28.48
Human Site:
T200
Identified Species:
44.76
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
T200
M
I
R
P
K
W
K
T
R
G
P
G
Y
T
Q
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
T200
M
I
R
P
K
W
K
T
R
G
P
G
Y
T
Q
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
T200
M
I
R
P
K
W
K
T
R
G
P
G
Y
T
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
S200
M
V
R
P
K
W
K
S
R
G
L
G
Y
T
Q
Rat
Rattus norvegicus
O54888
1135
127691
S200
M
I
R
P
K
W
K
S
R
G
L
G
Y
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
S211
L
I
R
P
K
W
K
S
R
G
P
G
Y
T
H
Chicken
Gallus gallus
XP_415007
1041
117633
V163
G
F
A
L
K
A
L
V
N
F
T
D
Y
Q
I
Frog
Xenopus laevis
NP_001080005
1134
128197
N200
M
I
R
P
K
W
K
N
R
G
P
G
Y
T
Q
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
S199
V
S
R
P
K
F
K
S
R
G
Q
G
Y
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
D199
V
K
R
S
S
W
K
D
R
G
Q
N
F
S
D
Honey Bee
Apis mellifera
XP_001120416
1121
127333
T192
I
K
R
S
G
W
K
T
R
G
I
Q
F
S
D
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
G219
Y
V
F
S
M
K
D
G
K
Y
A
F
K
T
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
N220
V
F
K
K
R
Q
P
N
K
Y
A
Y
V
G
E
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
N224
I
I
R
P
S
F
A
N
R
G
A
S
Y
S
H
Red Bread Mold
Neurospora crassa
O74633
1234
138583
N218
I
V
R
P
S
F
Q
N
R
G
A
S
Y
T
P
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
80
86.6
N.A.
80
13.3
93.3
66.6
N.A.
33.3
40
6.6
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
13.3
93.3
86.6
N.A.
53.3
60
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
0
40
40
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
60
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
7
0
0
0
27
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
7
0
0
0
7
0
0
14
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% E
% Phe:
0
14
7
0
0
20
0
0
0
7
0
7
14
0
0
% F
% Gly:
7
0
0
0
7
0
0
7
0
80
0
54
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
14
% H
% Ile:
20
47
0
0
0
0
0
0
0
0
7
0
0
0
7
% I
% Lys:
0
14
7
7
60
7
67
0
14
0
0
0
7
0
0
% K
% Leu:
7
0
0
7
0
0
7
0
0
0
14
0
0
0
0
% L
% Met:
40
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
27
7
0
0
7
0
0
0
% N
% Pro:
0
0
0
67
0
0
7
0
0
0
34
0
0
0
7
% P
% Gln:
0
0
0
0
0
7
7
0
0
0
14
7
0
7
47
% Q
% Arg:
0
0
80
0
7
0
0
0
80
0
0
0
0
0
0
% R
% Ser:
0
7
0
20
20
0
0
27
0
0
0
14
0
20
0
% S
% Thr:
0
0
0
0
0
0
0
27
0
0
7
0
0
67
0
% T
% Val:
20
20
0
0
0
0
0
7
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
14
0
7
74
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _