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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
33.64
Human Site:
T636
Identified Species:
52.86
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
T636
G
K
E
E
L
I
G
T
M
E
Q
I
F
M
N
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
T636
G
K
E
E
L
I
G
T
M
E
Q
I
F
M
N
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
T636
G
K
E
E
L
I
G
T
M
E
Q
I
F
M
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
T636
G
R
E
E
L
I
G
T
M
E
Q
L
F
M
N
Rat
Rattus norvegicus
O54888
1135
127691
A640
A
R
W
N
Y
G
A
A
L
H
E
H
C
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
T647
G
K
E
E
F
I
G
T
L
E
Q
T
F
M
N
Chicken
Gallus gallus
XP_415007
1041
117633
T562
S
D
V
M
P
G
V
T
T
H
Q
E
L
F
P
Frog
Xenopus laevis
NP_001080005
1134
128197
T635
G
K
E
E
L
L
G
T
L
E
Q
V
F
L
N
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
I634
G
K
Q
E
L
I
G
I
F
E
Q
V
Y
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
T634
K
R
V
E
Y
I
G
T
L
E
Q
L
Y
M
E
Honey Bee
Apis mellifera
XP_001120416
1121
127333
T629
K
N
I
E
Y
I
G
T
F
E
Q
I
Y
L
D
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
S675
G
V
V
E
L
I
D
S
M
E
E
E
T
S
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
T677
D
T
E
E
E
E
T
T
M
I
S
M
T
I
S
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
P666
D
K
E
D
I
V
G
P
F
E
Q
V
Y
M
N
Red Bread Mold
Neurospora crassa
O74633
1234
138583
P669
Q
K
E
D
F
V
G
P
Q
E
Q
P
Y
M
S
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
0
N.A.
80
13.3
73.3
60
N.A.
46.6
46.6
40
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
20
N.A.
86.6
13.3
100
86.6
N.A.
73.3
66.6
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
26.6
46.6
40
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
80
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
14
7
0
14
0
0
7
0
0
0
0
0
0
0
7
% D
% Glu:
0
0
60
74
7
7
0
0
0
80
14
14
0
0
7
% E
% Phe:
0
0
0
0
14
0
0
0
20
0
0
0
40
7
0
% F
% Gly:
54
0
0
0
0
14
74
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
14
0
7
0
7
0
% H
% Ile:
0
0
7
0
7
60
0
7
0
7
0
27
0
7
0
% I
% Lys:
14
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
47
7
0
0
27
0
0
14
7
20
7
% L
% Met:
0
0
0
7
0
0
0
0
40
0
0
7
0
54
7
% M
% Asn:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
54
% N
% Pro:
0
0
0
0
7
0
0
14
0
0
0
7
0
0
7
% P
% Gln:
7
0
7
0
0
0
0
0
7
0
80
0
0
0
0
% Q
% Arg:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
0
0
7
0
0
7
0
0
7
14
% S
% Thr:
0
7
0
0
0
0
7
67
7
0
0
7
14
0
0
% T
% Val:
0
7
20
0
0
14
7
0
0
0
0
20
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
20
0
0
0
0
0
0
0
34
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _