KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
20
Human Site:
Y24
Identified Species:
31.43
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
Y24
K
H
L
T
D
P
S
Y
G
I
P
R
E
Q
Q
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
Y24
K
H
L
T
D
P
S
Y
G
I
P
R
E
Q
Q
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
Y24
K
H
L
T
D
P
S
Y
G
I
P
R
E
Q
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
Y24
K
H
L
T
D
P
S
Y
G
I
P
P
E
Q
Q
Rat
Rattus norvegicus
O54888
1135
127691
Y24
K
H
L
T
D
P
S
Y
A
V
P
P
E
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
D35
L
H
V
T
R
P
E
D
G
A
P
R
A
R
Q
Chicken
Gallus gallus
XP_415007
1041
117633
I24
D
T
S
T
E
V
D
I
S
W
S
V
N
D
I
Frog
Xenopus laevis
NP_001080005
1134
128197
Y24
A
K
L
T
S
P
D
Y
G
I
P
G
E
S
Q
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
Q30
F
G
V
P
K
E
K
Q
R
V
P
V
Q
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
A33
K
K
L
S
R
H
L
A
N
L
G
G
P
H
V
Honey Bee
Apis mellifera
XP_001120416
1121
127333
Q26
E
K
Q
N
P
L
L
Q
R
L
G
A
P
H
I
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
L51
K
G
L
V
R
Q
Q
L
D
S
F
D
E
F
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
V29
T
Q
E
D
A
W
A
V
I
S
A
Y
F
E
E
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
N27
E
R
E
S
R
F
I
N
P
P
K
D
K
S
A
Red Bread Mold
Neurospora crassa
O74633
1234
138583
N51
D
P
H
I
E
S
F
N
A
L
F
R
D
D
G
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
80
N.A.
46.6
6.6
60
6.6
N.A.
13.3
0
20
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
86.6
N.A.
60
13.3
60
33.3
N.A.
26.6
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
0
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
7
7
14
7
7
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
7
34
0
14
7
7
0
0
14
7
14
0
% D
% Glu:
14
0
14
0
14
7
7
0
0
0
0
0
47
14
7
% E
% Phe:
7
0
0
0
0
7
7
0
0
0
14
0
7
7
0
% F
% Gly:
0
14
0
0
0
0
0
0
40
0
14
14
0
0
7
% G
% His:
0
40
7
0
0
7
0
0
0
0
0
0
0
14
0
% H
% Ile:
0
0
0
7
0
0
7
7
7
34
0
0
0
0
14
% I
% Lys:
47
20
0
0
7
0
7
0
0
0
7
0
7
0
0
% K
% Leu:
7
0
54
0
0
7
14
7
0
20
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
14
7
0
0
0
7
0
0
% N
% Pro:
0
7
0
7
7
47
0
0
7
7
54
14
14
0
0
% P
% Gln:
0
7
7
0
0
7
7
14
0
0
0
0
7
34
47
% Q
% Arg:
0
7
0
0
27
0
0
0
14
0
0
34
0
7
0
% R
% Ser:
0
0
7
14
7
7
34
0
7
14
7
0
0
14
0
% S
% Thr:
7
7
0
54
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
14
7
0
7
0
7
0
14
0
14
0
0
14
% V
% Trp:
0
0
0
0
0
7
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _