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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
25.45
Human Site:
Y318
Identified Species:
40
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
Y318
K
L
N
V
P
D
W
Y
P
N
E
Q
A
A
E
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
Y318
K
L
N
V
P
D
W
Y
P
N
E
Q
A
A
E
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
Y318
K
L
N
V
P
D
W
Y
P
N
E
Q
A
A
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
Y318
K
L
S
L
P
D
W
Y
P
N
V
E
A
A
E
Rat
Rattus norvegicus
O54888
1135
127691
Y318
K
L
S
L
P
D
W
Y
P
N
A
E
A
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
Y329
K
L
N
L
P
E
W
Y
R
N
E
Q
A
A
E
Chicken
Gallus gallus
XP_415007
1041
117633
E279
P
D
S
L
M
N
Q
E
V
L
T
A
G
Q
L
Frog
Xenopus laevis
NP_001080005
1134
128197
Y318
K
F
Y
L
P
E
W
Y
T
D
E
Q
A
A
E
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
F317
K
L
N
L
P
E
W
F
T
H
E
Q
C
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
W317
R
F
P
E
V
P
E
W
Q
P
D
D
D
V
T
Honey Bee
Apis mellifera
XP_001120416
1121
127333
D310
K
F
F
E
L
P
E
D
A
T
D
I
D
V
C
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
E339
A
K
P
G
V
T
R
E
Q
R
I
K
Y
A
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
E338
A
T
V
G
V
T
K
E
K
R
I
K
Y
A
R
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
P342
R
V
V
F
Q
A
S
P
D
Q
S
D
L
E
V
Red Bread Mold
Neurospora crassa
O74633
1234
138583
M340
V
L
G
V
P
D
T
M
S
D
Y
E
V
G
T
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
73.3
73.3
N.A.
80
0
60
53.3
N.A.
0
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
93.3
20
80
80
N.A.
20
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
0
7
0
0
7
0
7
7
47
67
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
0
7
0
0
0
40
0
7
7
14
14
14
14
0
0
% D
% Glu:
0
0
0
14
0
20
14
20
0
0
40
20
0
7
47
% E
% Phe:
0
20
7
7
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
14
0
0
0
0
0
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
14
7
0
0
0
% I
% Lys:
60
7
0
0
0
0
7
0
7
0
0
14
0
0
0
% K
% Leu:
0
54
0
40
7
0
0
0
0
7
0
0
7
0
7
% L
% Met:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
34
0
0
7
0
0
0
40
0
0
0
0
0
% N
% Pro:
7
0
14
0
60
14
0
7
34
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
7
0
14
7
0
40
0
7
0
% Q
% Arg:
14
0
0
0
0
0
7
0
7
14
0
0
0
0
14
% R
% Ser:
0
0
20
0
0
0
7
0
7
0
7
0
0
0
0
% S
% Thr:
0
7
0
0
0
14
7
0
14
7
7
0
0
0
14
% T
% Val:
7
7
14
27
20
0
0
0
7
0
7
0
7
14
7
% V
% Trp:
0
0
0
0
0
0
54
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
47
0
0
7
0
14
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _