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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
44.24
Human Site:
Y465
Identified Species:
69.52
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
Y465
D
K
L
N
F
I
R
Y
L
S
H
F
R
C
V
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
Y465
D
K
L
N
F
I
R
Y
L
S
H
F
R
C
V
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
Y465
D
K
L
N
F
I
R
Y
L
S
H
F
R
C
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
Y465
D
K
L
N
F
L
R
Y
L
S
H
F
R
C
V
Rat
Rattus norvegicus
O54888
1135
127691
Y465
D
K
L
N
F
I
R
Y
L
S
H
F
R
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
Y476
D
K
L
N
F
I
R
Y
L
S
H
F
R
C
V
Chicken
Gallus gallus
XP_415007
1041
117633
G415
T
P
D
G
E
P
C
G
L
M
N
H
M
T
A
Frog
Xenopus laevis
NP_001080005
1134
128197
Y464
D
K
L
N
F
I
R
Y
L
S
H
F
R
C
V
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
Y463
D
K
L
N
F
I
R
Y
L
S
H
F
R
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
Y465
E
N
I
N
R
M
R
Y
M
S
H
F
R
A
I
Honey Bee
Apis mellifera
XP_001120416
1121
127333
Y459
E
N
I
N
R
M
R
Y
M
S
H
F
R
A
I
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
T484
N
R
L
T
Y
T
A
T
L
S
H
L
R
R
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
T482
N
R
L
T
Y
A
S
T
L
S
H
L
R
R
L
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
F496
E
K
I
N
F
Y
R
F
I
S
H
F
R
M
V
Red Bread Mold
Neurospora crassa
O74633
1234
138583
F502
E
K
L
N
F
L
R
F
I
S
H
F
R
M
V
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
100
N.A.
100
6.6
100
100
N.A.
46.6
46.6
33.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
13.3
100
100
N.A.
80
80
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
33.3
60
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
60
86.6
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
7
0
0
0
0
0
0
14
14
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
54
0
% C
% Asp:
54
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
27
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
67
0
0
14
0
0
0
80
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
94
7
0
0
0
% H
% Ile:
0
0
20
0
0
47
0
0
14
0
0
0
0
0
14
% I
% Lys:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
74
0
0
14
0
0
74
0
0
14
0
0
7
% L
% Met:
0
0
0
0
0
14
0
0
14
7
0
0
7
14
0
% M
% Asn:
14
14
0
80
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
14
0
0
14
0
80
0
0
0
0
0
94
14
0
% R
% Ser:
0
0
0
0
0
0
7
0
0
94
0
0
0
0
0
% S
% Thr:
7
0
0
14
0
7
0
14
0
0
0
0
0
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
67
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
14
7
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _