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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
16.67
Human Site:
Y48
Identified Species:
26.19
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
Y48
A
H
V
E
S
F
N
Y
A
V
H
E
G
L
G
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
Y48
A
H
V
E
S
F
N
Y
A
V
H
E
G
L
G
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
Y48
A
H
V
E
S
F
N
Y
A
V
H
E
G
L
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
Y48
A
H
V
D
S
F
N
Y
A
A
L
E
G
L
S
Rat
Rattus norvegicus
O54888
1135
127691
Y48
A
H
V
D
S
F
N
Y
A
V
L
E
G
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
H59
A
H
V
R
S
F
D
H
A
V
R
E
G
L
S
Chicken
Gallus gallus
XP_415007
1041
117633
K48
G
F
V
P
I
M
V
K
S
K
L
C
N
L
Y
Frog
Xenopus laevis
NP_001080005
1134
128197
Q48
A
H
I
D
S
F
N
Q
A
M
T
E
G
L
S
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
C54
Q
A
V
T
D
G
L
C
R
V
V
E
A
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
H57
G
L
D
N
S
A
K
H
M
I
P
N
H
W
L
Honey Bee
Apis mellifera
XP_001120416
1121
127333
D50
G
L
C
K
A
V
K
D
N
P
H
V
Y
I
H
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
Q75
D
S
P
P
V
E
L
Q
S
E
N
Q
H
L
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
N53
S
F
D
E
F
I
Q
N
T
M
Q
E
I
V
D
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
A51
P
H
I
G
S
F
N
A
L
T
E
G
P
D
G
Red Bread Mold
Neurospora crassa
O74633
1234
138583
F75
A
E
I
G
T
K
T
F
L
D
G
D
E
R
A
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
73.3
80
N.A.
66.6
13.3
60
20
N.A.
6.6
6.6
13.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
80
86.6
N.A.
80
20
80
26.6
N.A.
20
26.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
13.3
33.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
40
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
7
0
0
7
7
0
7
47
7
0
0
7
0
7
% A
% Cys:
0
0
7
0
0
0
0
7
0
0
0
7
0
0
0
% C
% Asp:
7
0
14
20
7
0
7
7
0
7
0
7
0
7
7
% D
% Glu:
0
7
0
27
0
7
0
0
0
7
7
60
7
0
0
% E
% Phe:
0
14
0
0
7
54
0
7
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
14
0
7
0
0
0
0
7
7
47
0
34
% G
% His:
0
54
0
0
0
0
0
14
0
0
27
0
14
0
7
% H
% Ile:
0
0
20
0
7
7
0
0
0
7
0
0
7
14
0
% I
% Lys:
0
0
0
7
0
7
14
7
0
7
0
0
0
0
0
% K
% Leu:
0
14
0
0
0
0
14
0
14
0
20
0
0
60
7
% L
% Met:
0
0
0
0
0
7
0
0
7
14
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
47
7
7
0
7
7
7
0
0
% N
% Pro:
7
0
7
14
0
0
0
0
0
7
7
0
7
0
7
% P
% Gln:
7
0
0
0
0
0
7
14
0
0
7
7
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
7
0
7
0
0
7
0
% R
% Ser:
7
7
0
0
60
0
0
0
14
0
0
0
0
0
27
% S
% Thr:
0
0
0
7
7
0
7
0
7
7
7
0
0
0
0
% T
% Val:
0
0
54
0
7
7
7
0
0
40
7
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _