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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1B
All Species:
30.61
Human Site:
Y554
Identified Species:
48.1
UniProt:
Q9H9Y6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Y6
NP_001131076.1
1135
128229
Y554
H
R
S
Y
S
E
C
Y
P
V
L
L
D
G
V
Chimpanzee
Pan troglodytes
XP_515692
1135
128294
Y554
H
R
S
Y
S
E
C
Y
P
V
L
L
D
G
V
Rhesus Macaque
Macaca mulatta
XP_001088474
1135
128257
Y554
H
R
P
Y
S
E
C
Y
P
V
L
L
D
G
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70700
1135
127957
Y554
C
R
P
Y
S
D
C
Y
P
V
L
L
D
G
V
Rat
Rattus norvegicus
O54888
1135
127691
Y554
C
R
P
Y
S
D
C
Y
P
V
L
L
D
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515678
1146
129549
Y565
S
Q
P
Y
R
D
C
Y
P
V
V
L
D
G
V
Chicken
Gallus gallus
XP_415007
1041
117633
L503
P
S
R
A
E
V
V
L
I
P
M
T
G
K
P
Frog
Xenopus laevis
NP_001080005
1134
128197
Y553
G
K
S
F
A
D
C
Y
P
V
M
L
D
G
A
Zebra Danio
Brachydanio rerio
NP_956812
1132
127666
Y552
G
Q
A
Y
S
D
C
Y
P
V
I
L
D
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20028
1129
128426
L554
R
R
Y
L
G
E
K
L
Y
V
V
F
L
D
G
Honey Bee
Apis mellifera
XP_001120416
1121
127333
Y548
A
D
N
W
K
N
S
Y
I
V
M
L
D
G
K
Nematode Worm
Caenorhab. elegans
Q10578
1193
134886
K572
S
A
I
A
D
A
T
K
I
F
V
N
G
A
W
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P38420
1188
135001
K570
S
V
I
P
Q
A
T
K
I
F
V
N
G
M
W
Baker's Yeast
Sacchar. cerevisiae
P22138
1203
135723
C585
A
A
G
P
S
L
C
C
V
Q
I
D
G
K
I
Red Bread Mold
Neurospora crassa
O74633
1234
138583
M591
T
S
E
S
V
V
V
M
L
D
G
R
I
V
G
Conservation
Percent
Protein Identity:
100
99.5
98.6
N.A.
N.A.
89.6
85.2
N.A.
83.5
68.1
77
75.7
N.A.
45.2
47.1
28.3
N.A.
Protein Similarity:
100
99.8
99.5
N.A.
N.A.
95.4
90.3
N.A.
92.8
79.5
88.9
89.2
N.A.
64.9
66
44.9
N.A.
P-Site Identity:
100
100
93.3
N.A.
N.A.
80
80
N.A.
60
0
53.3
60
N.A.
20
33.3
0
N.A.
P-Site Similarity:
100
100
93.3
N.A.
N.A.
86.6
86.6
N.A.
80
6.6
86.6
86.6
N.A.
26.6
53.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.8
42.4
44
Protein Similarity:
N.A.
N.A.
N.A.
42.8
61.9
60.7
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
7
14
7
14
0
0
0
0
0
0
0
7
14
% A
% Cys:
14
0
0
0
0
0
60
7
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
7
34
0
0
0
7
0
7
60
7
0
% D
% Glu:
0
0
7
0
7
27
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
14
0
7
0
0
0
% F
% Gly:
14
0
7
0
7
0
0
0
0
0
7
0
27
60
14
% G
% His:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
14
0
0
0
0
0
27
0
14
0
7
0
7
% I
% Lys:
0
7
0
0
7
0
7
14
0
0
0
0
0
14
7
% K
% Leu:
0
0
0
7
0
7
0
14
7
0
34
60
7
0
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
20
0
0
7
0
% M
% Asn:
0
0
7
0
0
7
0
0
0
0
0
14
0
0
0
% N
% Pro:
7
0
27
14
0
0
0
0
54
7
0
0
0
0
7
% P
% Gln:
0
14
0
0
7
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
7
40
7
0
7
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
20
14
20
7
47
0
7
0
0
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
14
0
0
0
0
7
0
0
0
% T
% Val:
0
7
0
0
7
14
14
0
7
67
27
0
0
7
40
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
14
% W
% Tyr:
0
0
7
47
0
0
0
60
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _