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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIN28
All Species:
31.52
Human Site:
S106
Identified Species:
57.78
UniProt:
Q9H9Z2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H9Z2
NP_078950.1
209
22743
S106
K
S
A
K
G
L
E
S
I
R
V
T
G
P
G
Chimpanzee
Pan troglodytes
XP_513232
209
22865
S106
K
S
A
K
G
L
E
S
I
R
V
T
G
P
G
Rhesus Macaque
Macaca mulatta
XP_001114640
143
15918
C51
T
G
P
G
G
V
F
C
I
G
S
E
R
R
P
Dog
Lupus familis
XP_854985
206
22464
S102
K
S
A
K
G
L
E
S
I
R
V
T
G
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3Y3
209
22701
S106
K
S
A
K
G
L
E
S
I
R
V
T
G
P
G
Rat
Rattus norvegicus
P62961
322
35711
A120
E
G
E
K
G
A
E
A
A
N
V
T
G
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506004
274
29355
S116
K
S
S
K
G
L
E
S
I
R
V
T
G
P
G
Chicken
Gallus gallus
Q45KJ5
202
22071
S100
K
S
S
K
G
L
E
S
I
R
V
T
G
P
G
Frog
Xenopus laevis
Q8JHC4
195
21688
S100
K
S
S
K
G
L
E
S
T
Q
V
T
G
P
G
Zebra Danio
Brachydanio rerio
Q803L0
202
21867
S100
R
S
S
K
G
L
E
S
L
Q
V
T
G
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRN5
195
21575
A98
R
T
S
R
G
L
E
A
T
R
V
S
S
R
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P92186
227
25447
R112
E
R
S
N
G
K
G
R
E
A
Y
A
V
S
G
Sea Urchin
Strong. purpuratus
XP_792032
234
25286
A122
F
S
E
K
G
R
E
A
T
T
V
T
G
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
65.5
95.2
N.A.
96.6
20.8
N.A.
53.2
80.8
62.6
66.9
N.A.
34.9
N.A.
26.4
33.7
Protein Similarity:
100
98.5
67.4
96.6
N.A.
98.5
34.4
N.A.
60.2
87
74.1
79.4
N.A.
47.8
N.A.
44
47
P-Site Identity:
100
100
13.3
100
N.A.
100
53.3
N.A.
93.3
93.3
80
73.3
N.A.
33.3
N.A.
13.3
46.6
P-Site Similarity:
100
100
20
100
N.A.
100
66.6
N.A.
100
100
93.3
100
N.A.
73.3
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
0
0
8
0
24
8
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
16
0
16
0
0
0
85
0
8
0
0
8
0
0
0
% E
% Phe:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
0
8
100
0
8
0
0
8
0
0
77
0
77
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% I
% Lys:
54
0
0
77
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
70
0
0
8
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
70
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% Q
% Arg:
16
8
0
8
0
8
0
8
0
54
0
0
8
16
0
% R
% Ser:
0
70
47
0
0
0
0
62
0
0
8
8
8
8
0
% S
% Thr:
8
8
0
0
0
0
0
0
24
8
0
77
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
85
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _