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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D17
All Species:
22.73
Human Site:
S176
Identified Species:
45.45
UniProt:
Q9HA65
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HA65
NP_078958.1
648
72654
S176
S
R
Y
L
L
L
A
S
S
P
Q
D
S
R
L
Chimpanzee
Pan troglodytes
XP_001173398
648
72677
S176
S
R
Y
L
L
L
A
S
S
P
Q
D
S
R
L
Rhesus Macaque
Macaca mulatta
XP_001115627
648
72717
S176
S
R
Y
L
L
L
A
S
S
P
Q
D
S
R
L
Dog
Lupus familis
XP_541487
648
72599
S176
S
R
Y
L
L
L
A
S
S
P
Q
D
S
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYH7
645
72900
S175
S
R
Y
L
L
L
A
S
S
P
Q
D
S
R
L
Rat
Rattus norvegicus
NP_001099728
646
72777
S176
S
R
Y
L
L
L
A
S
S
P
Q
D
S
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512516
918
104718
E293
K
K
Y
V
V
L
C
E
S
S
Q
D
K
R
I
Chicken
Gallus gallus
NP_001012827
667
76877
E183
E
N
H
V
V
L
R
E
S
P
Q
D
K
L
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001166096
664
76835
E180
R
K
S
V
Q
I
N
E
S
P
D
D
E
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624756
650
75094
L163
V
D
E
V
Q
S
V
L
T
K
S
F
A
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190499
1259
155020
R820
E
K
Y
V
I
L
F
R
S
P
N
D
S
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P48365
746
87287
P197
P
E
F
W
L
V
N
P
S
L
N
D
L
R
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.4
93.2
N.A.
88.8
90.4
N.A.
37.3
47
N.A.
48.4
N.A.
N.A.
38
N.A.
23.4
Protein Similarity:
100
99.2
98.7
95.5
N.A.
92.4
93.5
N.A.
49.7
64.3
N.A.
65.5
N.A.
N.A.
55.6
N.A.
32.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
40
33.3
N.A.
20
N.A.
N.A.
6.6
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
66.6
60
N.A.
46.6
N.A.
N.A.
26.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
50
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
9
92
0
0
0
% D
% Glu:
17
9
9
0
0
0
0
25
0
0
0
0
9
9
0
% E
% Phe:
0
0
9
0
0
0
9
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
17
% I
% Lys:
9
25
0
0
0
0
0
0
0
9
0
0
17
0
0
% K
% Leu:
0
0
0
50
59
75
0
9
0
9
0
0
9
9
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
17
0
0
0
17
0
0
0
9
% N
% Pro:
9
0
0
0
0
0
0
9
0
75
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
67
0
0
0
0
% Q
% Arg:
9
50
0
0
0
0
9
9
0
0
0
0
0
75
0
% R
% Ser:
50
0
9
0
0
9
0
50
92
9
9
0
59
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
9
0
0
42
17
9
9
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _