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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D17 All Species: 37.58
Human Site: S177 Identified Species: 75.15
UniProt: Q9HA65 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HA65 NP_078958.1 648 72654 S177 R Y L L L A S S P Q D S R L Y
Chimpanzee Pan troglodytes XP_001173398 648 72677 S177 R Y L L L A S S P Q D S R L Y
Rhesus Macaque Macaca mulatta XP_001115627 648 72717 S177 R Y L L L A S S P Q D S R L Y
Dog Lupus familis XP_541487 648 72599 S177 R Y L L L A S S P Q D S R L Y
Cat Felis silvestris
Mouse Mus musculus Q8BYH7 645 72900 S176 R Y L L L A S S P Q D S R L Y
Rat Rattus norvegicus NP_001099728 646 72777 S177 R Y L L L A S S P Q D S R L Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512516 918 104718 S294 K Y V V L C E S S Q D K R I L
Chicken Gallus gallus NP_001012827 667 76877 S184 N H V V L R E S P Q D K L I L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001166096 664 76835 S181 K S V Q I N E S P D D E S V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624756 650 75094 T164 D E V Q S V L T K S F A E L D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190499 1259 155020 S821 K Y V I L F R S P N D S R L Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P48365 746 87287 S198 E F W L V N P S L N D L R N F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.4 93.2 N.A. 88.8 90.4 N.A. 37.3 47 N.A. 48.4 N.A. N.A. 38 N.A. 23.4
Protein Similarity: 100 99.2 98.7 95.5 N.A. 92.4 93.5 N.A. 49.7 64.3 N.A. 65.5 N.A. N.A. 55.6 N.A. 32.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 40 33.3 N.A. 20 N.A. N.A. 6.6 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 66.6 60 N.A. 46.6 N.A. N.A. 26.6 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 50 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 9 92 0 0 0 9 % D
% Glu: 9 9 0 0 0 0 25 0 0 0 0 9 9 0 0 % E
% Phe: 0 9 0 0 0 9 0 0 0 0 9 0 0 0 9 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 9 0 0 0 0 0 0 0 0 17 0 % I
% Lys: 25 0 0 0 0 0 0 0 9 0 0 17 0 0 0 % K
% Leu: 0 0 50 59 75 0 9 0 9 0 0 9 9 67 25 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 17 0 0 0 17 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 9 0 75 0 0 0 0 0 0 % P
% Gln: 0 0 0 17 0 0 0 0 0 67 0 0 0 0 0 % Q
% Arg: 50 0 0 0 0 9 9 0 0 0 0 0 75 0 0 % R
% Ser: 0 9 0 0 9 0 50 92 9 9 0 59 9 0 0 % S
% Thr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % T
% Val: 0 0 42 17 9 9 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 59 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _