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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D17
All Species:
15.76
Human Site:
S247
Identified Species:
31.52
UniProt:
Q9HA65
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HA65
NP_078958.1
648
72654
S247
P
Q
P
E
G
A
A
S
D
L
P
P
P
P
D
Chimpanzee
Pan troglodytes
XP_001173398
648
72677
S247
P
Q
P
E
G
A
A
S
D
L
P
P
P
P
D
Rhesus Macaque
Macaca mulatta
XP_001115627
648
72717
S247
P
Q
P
E
G
A
A
S
D
L
P
P
P
P
D
Dog
Lupus familis
XP_541487
648
72599
P247
P
H
P
E
G
A
S
P
D
L
P
P
P
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYH7
645
72900
S246
P
H
P
E
G
A
S
S
P
N
L
P
P
L
P
Rat
Rattus norvegicus
NP_001099728
646
72777
S247
P
H
P
E
G
A
S
S
P
D
L
P
P
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512516
918
104718
A376
W
R
G
S
D
P
S
A
H
H
R
P
P
S
E
Chicken
Gallus gallus
NP_001012827
667
76877
S255
S
T
Q
R
R
P
P
S
E
M
A
D
F
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001166096
664
76835
A255
Q
R
P
A
E
E
V
A
D
V
L
G
E
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624756
650
75094
P236
F
T
I
D
I
P
P
P
P
V
S
V
G
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190499
1259
155020
R890
L
L
P
I
N
T
H
R
P
S
D
E
Y
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P48365
746
87287
W303
A
R
V
Y
L
A
N
W
S
L
G
V
K
Q
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.4
93.2
N.A.
88.8
90.4
N.A.
37.3
47
N.A.
48.4
N.A.
N.A.
38
N.A.
23.4
Protein Similarity:
100
99.2
98.7
95.5
N.A.
92.4
93.5
N.A.
49.7
64.3
N.A.
65.5
N.A.
N.A.
55.6
N.A.
32.6
P-Site Identity:
100
100
100
80
N.A.
53.3
53.3
N.A.
13.3
6.6
N.A.
13.3
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
60
60
N.A.
40
26.6
N.A.
33.3
N.A.
N.A.
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
59
25
17
0
0
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
0
0
42
9
9
9
0
0
42
% D
% Glu:
0
0
0
50
9
9
0
0
9
0
0
9
9
0
17
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
9
0
50
0
0
0
0
0
9
9
9
0
9
% G
% His:
0
25
0
0
0
0
9
0
9
9
0
0
0
0
0
% H
% Ile:
0
0
9
9
9
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
9
9
0
0
9
0
0
0
0
42
25
0
0
34
0
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
9
0
0
9
0
0
0
0
9
% N
% Pro:
50
0
67
0
0
25
17
17
34
0
34
59
59
34
17
% P
% Gln:
9
25
9
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
25
0
9
9
0
0
9
0
0
9
0
0
0
0
% R
% Ser:
9
0
0
9
0
0
34
50
9
9
9
0
0
17
0
% S
% Thr:
0
17
0
0
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
9
0
0
17
0
17
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _