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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D17 All Species: 20.91
Human Site: S308 Identified Species: 41.82
UniProt: Q9HA65 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HA65 NP_078958.1 648 72654 S308 E L K N R I F S G G L S P S L
Chimpanzee Pan troglodytes XP_001173398 648 72677 S308 E L K N R I F S G G L S P S L
Rhesus Macaque Macaca mulatta XP_001115627 648 72717 S308 E L K N R I F S G G L S P G L
Dog Lupus familis XP_541487 648 72599 S308 V L K A R I F S G G L S P G L
Cat Felis silvestris
Mouse Mus musculus Q8BYH7 645 72900 S308 E L K N R I F S G G L S P G L
Rat Rattus norvegicus NP_001099728 646 72777 S309 E L K S R I F S G G L S P G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512516 918 104718 R452 S M K E K I F R G G L C H A V
Chicken Gallus gallus NP_001012827 667 76877 K325 Y I K Q S I F K G G L C H T L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001166096 664 76835 K322 H L K D A I F K G G L C H A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624756 650 75094 H297 E V K E V I F H G G I V P S L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190499 1259 155020 R940 E V L L R I F R G G L A P S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P48365 746 87287 H382 E V K D F I F H G G L E N D S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.4 93.2 N.A. 88.8 90.4 N.A. 37.3 47 N.A. 48.4 N.A. N.A. 38 N.A. 23.4
Protein Similarity: 100 99.2 98.7 95.5 N.A. 92.4 93.5 N.A. 49.7 64.3 N.A. 65.5 N.A. N.A. 55.6 N.A. 32.6
P-Site Identity: 100 100 93.3 80 N.A. 93.3 86.6 N.A. 40 46.6 N.A. 46.6 N.A. N.A. 60 N.A. 66.6
P-Site Similarity: 100 100 93.3 80 N.A. 93.3 93.3 N.A. 66.6 60 N.A. 66.6 N.A. N.A. 73.3 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 0 0 0 0 0 9 0 17 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % C
% Asp: 0 0 0 17 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 67 0 0 17 0 0 0 0 0 0 0 9 0 0 0 % E
% Phe: 0 0 0 0 9 0 100 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 100 100 0 0 0 34 0 % G
% His: 9 0 0 0 0 0 0 17 0 0 0 0 25 0 0 % H
% Ile: 0 9 0 0 0 100 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 92 0 9 0 0 17 0 0 0 0 0 0 0 % K
% Leu: 0 59 9 9 0 0 0 0 0 0 92 0 0 0 75 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 34 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % P
% Gln: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 59 0 0 17 0 0 0 0 0 0 0 % R
% Ser: 9 0 0 9 9 0 0 50 0 0 0 50 0 34 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % T
% Val: 9 25 0 0 9 0 0 0 0 0 0 9 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _