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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D17
All Species:
18.79
Human Site:
T274
Identified Species:
37.58
UniProt:
Q9HA65
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HA65
NP_078958.1
648
72654
T274
V
E
L
G
P
R
P
T
V
E
R
G
P
P
V
Chimpanzee
Pan troglodytes
XP_001173398
648
72677
T274
V
E
L
G
P
R
P
T
V
E
R
G
P
P
V
Rhesus Macaque
Macaca mulatta
XP_001115627
648
72717
T274
V
E
L
G
P
R
P
T
V
E
R
G
P
P
V
Dog
Lupus familis
XP_541487
648
72599
A274
V
E
L
G
P
R
P
A
V
E
R
A
P
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYH7
645
72900
T274
V
E
L
G
Q
R
P
T
V
E
R
A
P
P
V
Rat
Rattus norvegicus
NP_001099728
646
72777
T275
V
E
L
G
Q
R
P
T
V
E
R
A
P
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512516
918
104718
V418
I
D
L
G
E
R
P
V
V
Q
R
R
D
P
V
Chicken
Gallus gallus
NP_001012827
667
76877
E291
I
D
L
G
E
Q
P
E
V
S
R
R
E
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001166096
664
76835
E288
L
D
L
G
P
R
P
E
M
Q
R
T
G
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624756
650
75094
P263
V
V
L
P
P
R
P
P
C
P
R
G
T
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190499
1259
155020
Y915
N
L
Q
A
E
Q
G
Y
G
L
V
S
Q
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P48365
746
87287
T354
L
Q
R
Q
F
P
L
T
E
A
K
W
N
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.4
93.2
N.A.
88.8
90.4
N.A.
37.3
47
N.A.
48.4
N.A.
N.A.
38
N.A.
23.4
Protein Similarity:
100
99.2
98.7
95.5
N.A.
92.4
93.5
N.A.
49.7
64.3
N.A.
65.5
N.A.
N.A.
55.6
N.A.
32.6
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
53.3
46.6
N.A.
53.3
N.A.
N.A.
53.3
N.A.
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
73.3
66.6
N.A.
80
N.A.
N.A.
60
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
9
0
9
0
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
25
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
50
0
0
25
0
0
17
9
50
0
0
9
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
75
0
0
9
0
9
0
0
34
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
17
9
84
0
0
0
9
0
0
9
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
9
50
9
84
9
0
9
0
0
50
84
0
% P
% Gln:
0
9
9
9
17
17
0
0
0
17
0
0
9
0
9
% Q
% Arg:
0
0
9
0
0
75
0
0
0
0
84
17
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
9
0
9
0
17
0
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
0
9
9
0
0
% T
% Val:
59
9
0
0
0
0
0
9
67
0
9
0
0
0
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _