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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D17 All Species: 33.64
Human Site: T282 Identified Species: 67.27
UniProt: Q9HA65 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HA65 NP_078958.1 648 72654 T282 V E R G P P V T E E E W A R H
Chimpanzee Pan troglodytes XP_001173398 648 72677 T282 V E R G P P V T E E E W A R H
Rhesus Macaque Macaca mulatta XP_001115627 648 72717 T282 V E R G P P V T E E E W A R H
Dog Lupus familis XP_541487 648 72599 T282 V E R A P P V T E E E W T H H
Cat Felis silvestris
Mouse Mus musculus Q8BYH7 645 72900 T282 V E R A P P V T E E E W N R Y
Rat Rattus norvegicus NP_001099728 646 72777 T283 V E R A P P V T E E E W N R H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512516 918 104718 S426 V Q R R D P V S F E E W N K S
Chicken Gallus gallus NP_001012827 667 76877 S299 V S R R E P V S I E E W T K N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001166096 664 76835 T296 M Q R T G P V T M E E W A K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624756 650 75094 S271 C P R G T P L S Q E Q W N K Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190499 1259 155020 D923 G L V S Q S Q D K E S R I T K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P48365 746 87287 W362 E A K W N S L W D E N D G R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.4 93.2 N.A. 88.8 90.4 N.A. 37.3 47 N.A. 48.4 N.A. N.A. 38 N.A. 23.4
Protein Similarity: 100 99.2 98.7 95.5 N.A. 92.4 93.5 N.A. 49.7 64.3 N.A. 65.5 N.A. N.A. 55.6 N.A. 32.6
P-Site Identity: 100 100 100 80 N.A. 80 86.6 N.A. 46.6 46.6 N.A. 53.3 N.A. N.A. 33.3 N.A. 6.6
P-Site Similarity: 100 100 100 80 N.A. 86.6 86.6 N.A. 66.6 66.6 N.A. 80 N.A. N.A. 73.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 25 0 0 0 0 0 0 0 0 34 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 9 9 0 0 9 0 0 0 % D
% Glu: 9 50 0 0 9 0 0 0 50 100 75 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 9 0 0 34 9 0 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 42 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 9 0 0 0 0 34 9 % K
% Leu: 0 9 0 0 0 0 17 0 0 0 0 0 0 0 9 % L
% Met: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 9 0 34 0 9 % N
% Pro: 0 9 0 0 50 84 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 17 0 0 9 0 9 0 9 0 9 0 0 0 0 % Q
% Arg: 0 0 84 17 0 0 0 0 0 0 0 9 0 50 0 % R
% Ser: 0 9 0 9 0 17 0 25 0 0 9 0 0 0 9 % S
% Thr: 0 0 0 9 9 0 0 59 0 0 0 0 17 9 0 % T
% Val: 67 0 9 0 0 0 75 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 9 0 0 0 84 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _