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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D17 All Species: 10.61
Human Site: T625 Identified Species: 21.21
UniProt: Q9HA65 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HA65 NP_078958.1 648 72654 T625 P P T P P P S T D T A P Q P D
Chimpanzee Pan troglodytes XP_001173398 648 72677 T625 P P T P P P S T D T A P Q A D
Rhesus Macaque Macaca mulatta XP_001115627 648 72717 T625 P P T P P P P T D T A Q Q P D
Dog Lupus familis XP_541487 648 72599 E625 P P A P P P P E D T A P Q P D
Cat Felis silvestris
Mouse Mus musculus Q8BYH7 645 72900 P622 T R A P L P P P L P E E V I P
Rat Rattus norvegicus NP_001099728 646 72777 P621 S P T R A P M P P P P P E E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512516 918 104718 V825 I L R N K P D V D L V F S V K
Chicken Gallus gallus NP_001012827 667 76877 V645 Y Q N I S T P V I A A N G T R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001166096 664 76835 P633 L E S P Q T S P R S S H R Q D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624756 650 75094 T612 N I E T D E A T N N S R R S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190499 1259 155020 D1237 D R N R G G G D E A R S D C S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P48365 746 87287 S721 T G V L P C Q S E R L T L L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 98.4 93.2 N.A. 88.8 90.4 N.A. 37.3 47 N.A. 48.4 N.A. N.A. 38 N.A. 23.4
Protein Similarity: 100 99.2 98.7 95.5 N.A. 92.4 93.5 N.A. 49.7 64.3 N.A. 65.5 N.A. N.A. 55.6 N.A. 32.6
P-Site Identity: 100 93.3 86.6 80 N.A. 13.3 26.6 N.A. 13.3 6.6 N.A. 20 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 93.3 86.6 80 N.A. 13.3 33.3 N.A. 13.3 6.6 N.A. 46.6 N.A. N.A. 33.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 9 0 9 0 0 17 42 0 0 9 0 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 0 % C
% Asp: 9 0 0 0 9 0 9 9 42 0 0 0 9 0 42 % D
% Glu: 0 9 9 0 0 9 0 9 17 0 9 9 9 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 9 0 0 9 9 9 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 9 9 0 9 0 0 0 0 9 0 0 0 0 9 0 % I
% Lys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 9 9 0 9 9 0 0 0 9 9 9 0 9 9 9 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 17 9 0 0 0 0 9 9 0 9 0 0 0 % N
% Pro: 34 42 0 50 42 59 34 25 9 17 9 34 0 25 9 % P
% Gln: 0 9 0 0 9 0 9 0 0 0 0 9 34 9 0 % Q
% Arg: 0 17 9 17 0 0 0 0 9 9 9 9 17 0 9 % R
% Ser: 9 0 9 0 9 0 25 9 0 9 17 9 9 9 17 % S
% Thr: 17 0 34 9 0 17 0 34 0 34 0 9 0 9 0 % T
% Val: 0 0 9 0 0 0 0 17 0 0 9 0 9 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _