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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALHM2
All Species:
21.52
Human Site:
S170
Identified Species:
59.17
UniProt:
Q9HA72
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HA72
NP_057000.2
323
36175
S170
K
E
N
P
D
N
L
S
D
F
R
E
E
V
S
Chimpanzee
Pan troglodytes
XP_001135702
323
36142
S170
K
E
N
P
D
N
L
S
D
F
R
E
E
V
S
Rhesus Macaque
Macaca mulatta
XP_001113788
323
36102
S170
K
E
N
P
D
N
L
S
D
F
R
E
E
V
S
Dog
Lupus familis
XP_544000
323
35848
S170
G
E
G
P
A
N
L
S
G
F
R
E
E
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEC4
323
35805
S170
G
E
G
P
A
N
L
S
S
F
R
E
E
V
S
Rat
Rattus norvegicus
Q5RJQ8
323
35913
S170
G
E
G
P
A
N
L
S
G
F
R
E
E
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512066
323
35596
S170
G
E
A
P
A
N
L
S
G
S
Q
A
E
V
V
Chicken
Gallus gallus
XP_001234076
319
35775
R169
P
A
N
L
T
K
F
R
D
E
V
T
R
R
L
Frog
Xenopus laevis
NP_001086556
319
35970
K169
P
K
E
L
I
P
F
K
D
E
V
I
R
R
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99
91.9
N.A.
92.2
92.2
N.A.
85.1
78.6
67.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.6
94.7
N.A.
95
94.1
N.A.
89.1
88.5
79.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
73.3
73.3
N.A.
46.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
73.3
N.A.
53.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
45
0
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
34
0
0
0
56
0
0
0
0
0
0
% D
% Glu:
0
78
12
0
0
0
0
0
0
23
0
67
78
0
0
% E
% Phe:
0
0
0
0
0
0
23
0
0
67
0
0
0
0
0
% F
% Gly:
45
0
34
0
0
0
0
0
34
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
34
12
0
0
0
12
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
23
0
0
78
0
0
0
0
0
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
45
0
0
78
0
0
0
0
0
0
0
0
0
% N
% Pro:
23
0
0
78
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
67
0
23
23
0
% R
% Ser:
0
0
0
0
0
0
0
78
12
12
0
0
0
0
56
% S
% Thr:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
0
23
0
0
78
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _