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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARS2
All Species:
24.85
Human Site:
S199
Identified Species:
49.7
UniProt:
Q9HA77
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HA77
NP_078813.1
564
62224
S199
N
V
Y
F
D
L
K
S
R
G
D
K
Y
G
K
Chimpanzee
Pan troglodytes
XP_509736
599
66308
S199
N
V
Y
F
D
L
K
S
R
G
D
K
Y
G
K
Rhesus Macaque
Macaca mulatta
XP_001083821
563
62194
S198
N
V
Y
F
D
L
K
S
R
G
D
K
Y
G
K
Dog
Lupus familis
XP_534184
628
68783
S264
N
V
Y
F
D
L
Q
S
R
G
D
K
Y
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYM8
551
61253
A184
S
V
Y
F
D
L
H
A
R
G
D
K
Y
G
K
Rat
Rattus norvegicus
NP_001171155
550
60899
A184
S
V
Y
F
D
L
R
A
R
G
D
K
Y
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514971
522
59156
A181
D
F
A
L
W
K
A
A
K
P
Q
E
I
F
W
Chicken
Gallus gallus
XP_416955
624
69782
S187
N
V
Y
F
D
V
N
S
W
G
E
R
Y
G
V
Frog
Xenopus laevis
Q6PA41
572
64760
S202
N
V
Y
F
D
V
Q
S
I
G
D
Q
Y
G
K
Zebra Danio
Brachydanio rerio
XP_682732
566
63916
S201
N
V
Y
F
N
T
K
S
I
S
H
R
Y
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610930
558
63512
K195
S
V
Y
F
D
V
S
K
S
K
N
Y
G
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796899
523
60081
L181
T
L
E
R
Y
D
K
L
A
S
Q
D
L
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
94.3
68.1
N.A.
77.1
76.9
N.A.
66.4
58
61.3
56.3
N.A.
38.1
N.A.
N.A.
43.9
Protein Similarity:
100
87.6
96.2
76.4
N.A.
85.1
84.9
N.A.
75.7
68.7
73.7
71.9
N.A.
53.1
N.A.
N.A.
59.2
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
0
60
73.3
60
N.A.
26.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
26.6
80
93.3
73.3
N.A.
46.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
9
25
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
75
9
0
0
0
0
59
9
0
9
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% E
% Phe:
0
9
0
84
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
67
0
0
9
75
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
17
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
9
42
9
9
9
0
50
0
9
67
% K
% Leu:
0
9
0
9
0
50
0
9
0
0
0
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
59
0
0
0
9
0
9
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
17
0
0
0
17
9
0
0
0
% Q
% Arg:
0
0
0
9
0
0
9
0
50
0
0
17
0
0
0
% R
% Ser:
25
0
0
0
0
0
9
59
9
17
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
0
84
0
0
0
25
0
0
0
0
0
0
0
0
17
% V
% Trp:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
9
% W
% Tyr:
0
0
84
0
9
0
0
0
0
0
0
9
75
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _