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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARS2
All Species:
18.79
Human Site:
S227
Identified Species:
37.58
UniProt:
Q9HA77
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HA77
NP_078813.1
564
62224
S227
D
S
D
K
R
H
A
S
D
F
A
L
W
K
A
Chimpanzee
Pan troglodytes
XP_509736
599
66308
L227
L
S
R
E
Q
Y
S
L
N
L
C
L
W
M
T
Rhesus Macaque
Macaca mulatta
XP_001083821
563
62194
S226
D
S
D
K
R
H
A
S
D
F
A
L
W
K
A
Dog
Lupus familis
XP_534184
628
68783
S292
D
S
D
K
R
H
A
S
D
F
A
L
W
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYM8
551
61253
S212
D
S
D
K
R
H
S
S
D
F
A
L
W
K
A
Rat
Rattus norvegicus
NP_001171155
550
60899
S213
D
S
D
K
R
H
S
S
D
F
A
L
W
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514971
522
59156
S208
I
E
C
S
T
I
S
S
L
I
F
G
S
Q
L
Chicken
Gallus gallus
XP_416955
624
69782
R215
D
T
D
K
R
H
G
R
D
F
A
L
W
K
A
Frog
Xenopus laevis
Q6PA41
572
64760
R230
L
Q
D
K
R
H
I
R
D
F
A
L
W
K
T
Zebra Danio
Brachydanio rerio
XP_682732
566
63916
R228
V
Q
D
K
E
N
S
R
D
F
A
L
W
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610930
558
63512
A223
K
R
N
T
A
D
F
A
L
W
K
A
R
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796899
523
60081
F207
E
K
R
H
P
R
D
F
A
L
W
K
G
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
94.3
68.1
N.A.
77.1
76.9
N.A.
66.4
58
61.3
56.3
N.A.
38.1
N.A.
N.A.
43.9
Protein Similarity:
100
87.6
96.2
76.4
N.A.
85.1
84.9
N.A.
75.7
68.7
73.7
71.9
N.A.
53.1
N.A.
N.A.
59.2
P-Site Identity:
100
20
100
100
N.A.
93.3
86.6
N.A.
6.6
80
66.6
60
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
53.3
100
100
N.A.
100
93.3
N.A.
20
86.6
66.6
73.3
N.A.
33.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
25
9
9
0
67
9
0
0
50
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
50
0
67
0
0
9
9
0
67
0
0
0
0
0
0
% D
% Glu:
9
9
0
9
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
67
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
9
9
0
9
% G
% His:
0
0
0
9
0
59
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
9
9
0
0
9
0
0
0
0
0
% I
% Lys:
9
9
0
67
0
0
0
0
0
0
9
9
0
75
9
% K
% Leu:
17
0
0
0
0
0
0
9
17
17
0
75
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
0
9
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
9
17
0
59
9
0
25
0
0
0
0
9
0
0
% R
% Ser:
0
50
0
9
0
0
42
50
0
0
0
0
9
0
9
% S
% Thr:
0
9
0
9
9
0
0
0
0
0
0
0
0
0
17
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
9
0
75
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _