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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARS2
All Species:
23.94
Human Site:
S401
Identified Species:
47.88
UniProt:
Q9HA77
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HA77
NP_078813.1
564
62224
S401
M
L
W
E
R
L
S
S
T
K
R
A
V
K
A
Chimpanzee
Pan troglodytes
XP_509736
599
66308
S406
M
L
W
E
R
L
S
S
T
K
R
A
V
K
A
Rhesus Macaque
Macaca mulatta
XP_001083821
563
62194
S400
M
L
W
E
R
L
A
S
T
R
S
A
V
K
E
Dog
Lupus familis
XP_534184
628
68783
H466
V
L
W
E
R
L
C
H
T
Q
E
A
V
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYM8
551
61253
S386
V
L
W
E
R
L
T
S
T
K
K
A
V
K
A
Rat
Rattus norvegicus
NP_001171155
550
60899
S387
V
L
W
E
R
L
A
S
T
K
K
A
V
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514971
522
59156
A368
D
T
R
R
A
V
D
A
I
M
D
L
I
R
H
Chicken
Gallus gallus
XP_416955
624
69782
S389
V
L
W
E
R
L
A
S
T
K
V
N
V
K
A
Frog
Xenopus laevis
Q6PA41
572
64760
E404
L
L
W
Q
R
L
N
E
T
K
V
N
V
K
A
Zebra Danio
Brachydanio rerio
XP_682732
566
63916
N402
F
L
W
E
R
L
S
N
T
Q
T
S
V
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610930
558
63512
H396
A
L
K
A
Q
L
T
H
T
V
T
E
F
D
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796899
523
60081
T379
E
L
M
Q
R
L
E
T
T
R
E
E
V
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
94.3
68.1
N.A.
77.1
76.9
N.A.
66.4
58
61.3
56.3
N.A.
38.1
N.A.
N.A.
43.9
Protein Similarity:
100
87.6
96.2
76.4
N.A.
85.1
84.9
N.A.
75.7
68.7
73.7
71.9
N.A.
53.1
N.A.
N.A.
59.2
P-Site Identity:
100
100
73.3
66.6
N.A.
80
80
N.A.
0
73.3
60
53.3
N.A.
20
N.A.
N.A.
33.3
P-Site Similarity:
100
100
86.6
80
N.A.
100
100
N.A.
26.6
86.6
80
73.3
N.A.
33.3
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
9
0
25
9
0
0
0
50
0
0
59
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
9
0
0
0
9
0
0
9
0
% D
% Glu:
9
0
0
67
0
0
9
9
0
0
17
17
0
0
17
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
17
0
0
0
0
0
9
9
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
9
9
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
50
17
0
0
67
9
% K
% Leu:
9
92
0
0
0
92
0
0
0
0
0
9
0
0
0
% L
% Met:
25
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
9
0
0
0
17
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
17
9
0
0
0
0
17
0
0
0
0
0
% Q
% Arg:
0
0
9
9
84
0
0
0
0
17
17
0
0
9
0
% R
% Ser:
0
0
0
0
0
0
25
50
0
0
9
9
0
0
0
% S
% Thr:
0
9
0
0
0
0
17
9
92
0
17
0
0
0
0
% T
% Val:
34
0
0
0
0
9
0
0
0
9
17
0
84
0
0
% V
% Trp:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _