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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARS2
All Species:
31.21
Human Site:
S446
Identified Species:
62.42
UniProt:
Q9HA77
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HA77
NP_078813.1
564
62224
S446
K
E
P
E
G
P
R
S
P
A
V
F
G
A
I
Chimpanzee
Pan troglodytes
XP_509736
599
66308
S451
K
E
P
G
G
P
R
S
P
A
V
F
G
A
I
Rhesus Macaque
Macaca mulatta
XP_001083821
563
62194
S445
K
E
P
G
V
P
R
S
P
A
V
F
G
A
I
Dog
Lupus familis
XP_534184
628
68783
S511
K
E
P
G
G
P
R
S
P
A
V
F
G
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYM8
551
61253
S431
K
E
A
S
G
P
R
S
P
T
V
F
G
A
I
Rat
Rattus norvegicus
NP_001171155
550
60899
S432
K
E
A
G
G
P
R
S
P
T
V
F
G
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514971
522
59156
C407
V
S
F
I
Q
E
F
C
D
T
F
G
I
S
L
Chicken
Gallus gallus
XP_416955
624
69782
S434
K
D
A
V
S
P
R
S
S
V
V
Y
G
S
I
Frog
Xenopus laevis
Q6PA41
572
64760
S449
K
E
S
S
S
P
R
S
P
I
V
Y
G
A
M
Zebra Danio
Brachydanio rerio
XP_682732
566
63916
S446
T
K
V
D
G
P
R
S
P
A
V
F
G
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610930
558
63512
C443
A
Q
E
E
P
A
Y
C
I
D
L
L
L
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796899
523
60081
S418
N
F
S
Q
V
S
E
S
T
Q
L
D
Q
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
94.3
68.1
N.A.
77.1
76.9
N.A.
66.4
58
61.3
56.3
N.A.
38.1
N.A.
N.A.
43.9
Protein Similarity:
100
87.6
96.2
76.4
N.A.
85.1
84.9
N.A.
75.7
68.7
73.7
71.9
N.A.
53.1
N.A.
N.A.
59.2
P-Site Identity:
100
93.3
86.6
86.6
N.A.
80
80
N.A.
0
46.6
60
73.3
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
86.6
93.3
N.A.
80
80
N.A.
13.3
66.6
73.3
86.6
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
25
0
0
9
0
0
0
42
0
0
0
67
9
% A
% Cys:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
0
0
0
9
9
0
9
0
0
0
% D
% Glu:
0
59
9
17
0
9
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
9
0
0
0
9
0
0
0
9
59
0
0
0
% F
% Gly:
0
0
0
34
50
0
0
0
0
0
0
9
75
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
9
9
0
0
9
0
67
% I
% Lys:
67
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
17
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
34
0
9
75
0
0
67
0
0
0
0
0
0
% P
% Gln:
0
9
0
9
9
0
0
0
0
9
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
17
17
17
9
0
84
9
0
0
0
0
34
9
% S
% Thr:
9
0
0
0
0
0
0
0
9
25
0
0
0
0
0
% T
% Val:
9
0
9
9
17
0
0
0
0
9
75
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _