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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CARS2
All Species:
33.03
Human Site:
Y355
Identified Species:
66.06
UniProt:
Q9HA77
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HA77
NP_078813.1
564
62224
Y355
S
Y
R
S
A
I
D
Y
S
D
S
A
M
L
Q
Chimpanzee
Pan troglodytes
XP_509736
599
66308
Y360
S
Y
R
S
A
I
D
Y
S
D
S
A
M
L
Q
Rhesus Macaque
Macaca mulatta
XP_001083821
563
62194
Y354
S
Y
R
S
A
I
D
Y
S
D
S
A
M
L
H
Dog
Lupus familis
XP_534184
628
68783
Y420
S
Y
R
A
A
I
D
Y
S
D
G
T
M
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYM8
551
61253
Y340
N
Y
R
S
A
I
E
Y
S
D
S
T
L
V
E
Rat
Rattus norvegicus
NP_001171155
550
60899
Y341
N
Y
R
S
A
I
D
Y
S
D
S
T
L
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514971
522
59156
D322
G
M
S
S
F
I
S
D
A
R
D
Y
M
R
G
Chicken
Gallus gallus
XP_416955
624
69782
F343
R
Y
S
S
A
V
E
F
S
D
E
T
M
N
D
Frog
Xenopus laevis
Q6PA41
572
64760
Y358
K
Y
K
S
A
V
E
Y
S
K
E
S
M
H
D
Zebra Danio
Brachydanio rerio
XP_682732
566
63916
Y356
K
Y
R
S
A
I
D
Y
S
D
A
S
M
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610930
558
63512
Y350
N
Y
R
N
A
M
P
Y
S
D
Q
L
M
V
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796899
523
60081
Y333
K
Y
D
H
D
L
E
Y
G
P
D
T
M
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
94.3
68.1
N.A.
77.1
76.9
N.A.
66.4
58
61.3
56.3
N.A.
38.1
N.A.
N.A.
43.9
Protein Similarity:
100
87.6
96.2
76.4
N.A.
85.1
84.9
N.A.
75.7
68.7
73.7
71.9
N.A.
53.1
N.A.
N.A.
59.2
P-Site Identity:
100
100
93.3
73.3
N.A.
60
66.6
N.A.
20
40
40
66.6
N.A.
46.6
N.A.
N.A.
26.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
93.3
86.6
N.A.
26.6
60
66.6
86.6
N.A.
73.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
84
0
0
0
9
0
9
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
9
0
50
9
0
75
17
0
0
0
17
% D
% Glu:
0
0
0
0
0
0
34
0
0
0
17
0
0
9
34
% E
% Phe:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
0
9
0
9
0
0
0
9
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
9
% H
% Ile:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% I
% Lys:
25
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
0
9
17
34
0
% L
% Met:
0
9
0
0
0
9
0
0
0
0
0
0
84
0
0
% M
% Asn:
25
0
0
9
0
0
0
0
0
0
0
0
0
17
0
% N
% Pro:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
25
% Q
% Arg:
9
0
67
0
0
0
0
0
0
9
0
0
0
9
0
% R
% Ser:
34
0
17
75
0
0
9
0
84
0
42
17
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
9
% T
% Val:
0
0
0
0
0
17
0
0
0
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
92
0
0
0
0
0
84
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _