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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LASS4 All Species: 8.48
Human Site: Y257 Identified Species: 18.67
UniProt: Q9HA82 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HA82 NP_078828.2 394 46399 Y257 K M V N Y M Q Y Q Q V C D A L
Chimpanzee Pan troglodytes XP_001157082 394 46430 Y257 K M V N Y M Q Y Q Q V C D A L
Rhesus Macaque Macaca mulatta XP_001093577 394 46363 Y257 K M V N Y T Q Y Q H V C D A L
Dog Lupus familis XP_542126 433 50637 W297 K M F N Y T P W R K V C D T L
Cat Felis silvestris
Mouse Mus musculus Q9D6J1 393 45998 F257 K I L N Y A H F R R G C D A L
Rat Rattus norvegicus NP_001100587 393 45986 F257 K M L N Y A H F Q R G C D T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519463 337 40397 H213 F K E Q I I H H F V T I T L M
Chicken Gallus gallus XP_418172 405 48252 W264 K I F N Y M K W K K T C D S L
Frog Xenopus laevis NP_001085735 372 43975 D243 L L V H D V S D I L L E A A K
Zebra Danio Brachydanio rerio XP_693668 383 45173 W257 K M F N Y A R W K N A C N Y I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDF2 310 36479 I186 L T R A G S V I L A L H D A S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 93.4 69 N.A. 69.2 69.8 N.A. 55 50.1 41.8 45.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.7 95.4 78 N.A. 82.9 82.2 N.A. 67.5 66.4 60.1 64.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 53.3 N.A. 46.6 53.3 N.A. 0 46.6 13.3 33.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 73.3 N.A. 80 73.3 N.A. 20 86.6 40 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 46.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 28 0 0 0 10 10 0 10 55 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 73 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 10 0 0 0 0 73 0 0 % D
% Glu: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 10 0 28 0 0 0 0 19 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 0 0 19 0 0 0 0 % G
% His: 0 0 0 10 0 0 28 10 0 10 0 10 0 0 0 % H
% Ile: 0 19 0 0 10 10 0 10 10 0 0 10 0 0 10 % I
% Lys: 73 10 0 0 0 0 10 0 19 19 0 0 0 0 10 % K
% Leu: 19 10 19 0 0 0 0 0 10 10 19 0 0 10 64 % L
% Met: 0 55 0 0 0 28 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 73 0 0 0 0 0 10 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 28 0 37 19 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 10 0 19 19 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 10 0 0 0 0 0 0 10 10 % S
% Thr: 0 10 0 0 0 19 0 0 0 0 19 0 10 19 0 % T
% Val: 0 0 37 0 0 10 10 0 0 10 37 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 73 0 0 28 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _