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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB1
All Species:
21.21
Human Site:
T12
Identified Species:
38.89
UniProt:
Q9HAE3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAE3
NP_078869.1
211
24488
T12
K
L
Q
K
L
T
D
T
L
T
K
N
C
K
H
Chimpanzee
Pan troglodytes
XP_528130
211
24456
T12
K
L
Q
K
L
T
D
T
L
T
K
N
C
K
H
Rhesus Macaque
Macaca mulatta
XP_001101162
211
24440
T12
K
L
Q
K
L
T
D
T
L
A
K
N
C
K
H
Dog
Lupus familis
XP_535064
271
31102
T71
K
L
Q
K
L
T
D
T
L
T
K
N
C
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3N2
212
24588
T12
K
L
Q
K
L
T
D
T
L
T
K
N
C
K
H
Rat
Rattus norvegicus
P84076
193
22409
E11
Q
N
S
K
L
R
P
E
M
L
Q
D
L
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520613
219
24982
S23
N
I
Q
K
L
A
E
S
L
S
K
G
L
K
H
Chicken
Gallus gallus
P42324
193
22251
E11
Q
N
S
K
L
R
P
E
V
L
Q
D
L
R
E
Frog
Xenopus laevis
Q3KQ77
208
24147
A12
N
L
Q
K
Q
A
E
A
L
S
R
L
I
K
H
Zebra Danio
Brachydanio rerio
Q6AXL4
192
21965
V12
N
S
K
L
R
P
E
V
I
Q
D
L
L
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42325
190
21875
E11
Q
N
S
K
L
K
P
E
V
L
E
D
L
K
Q
Honey Bee
Apis mellifera
XP_394805
307
34765
V21
R
M
E
R
G
S
G
V
S
V
D
V
G
V
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25296
175
19620
G11
A
P
S
K
I
V
D
G
L
L
E
D
T
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98
70.8
N.A.
91.5
24.6
N.A.
66.6
23.2
68.2
24.6
N.A.
21.3
34.8
N.A.
N.A.
Protein Similarity:
100
100
98.5
74.9
N.A.
94.8
46.9
N.A.
79.4
44.5
79.1
45.5
N.A.
42.6
48.5
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
100
13.3
N.A.
46.6
13.3
40
0
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
46.6
N.A.
73.3
46.6
60
26.6
N.A.
46.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
16
0
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% C
% Asp:
0
0
0
0
0
0
47
0
0
0
16
31
0
8
0
% D
% Glu:
0
0
8
0
0
0
24
24
0
0
16
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
8
0
8
8
0
0
0
8
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
47
% H
% Ile:
0
8
0
0
8
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
39
0
8
85
0
8
0
0
0
0
47
0
0
62
0
% K
% Leu:
0
47
0
8
70
0
0
0
62
31
0
16
39
0
0
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
24
24
0
0
0
0
0
0
0
0
0
39
0
8
16
% N
% Pro:
0
8
0
0
0
8
24
0
0
0
0
0
0
0
0
% P
% Gln:
24
0
54
0
8
0
0
0
0
8
16
0
0
0
8
% Q
% Arg:
8
0
0
8
8
16
0
0
0
0
8
0
0
16
0
% R
% Ser:
0
8
31
0
0
8
0
8
8
16
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
39
0
39
0
31
0
0
8
0
0
% T
% Val:
0
0
0
0
0
8
0
16
16
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _