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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFCAB1 All Species: 20
Human Site: T14 Identified Species: 36.67
UniProt: Q9HAE3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAE3 NP_078869.1 211 24488 T14 Q K L T D T L T K N C K H F N
Chimpanzee Pan troglodytes XP_528130 211 24456 T14 Q K L T D T L T K N C K H F N
Rhesus Macaque Macaca mulatta XP_001101162 211 24440 A14 Q K L T D T L A K N C K H F N
Dog Lupus familis XP_535064 271 31102 T73 Q K L T D T L T K N C K N F N
Cat Felis silvestris
Mouse Mus musculus Q9D3N2 212 24588 T14 Q K L T D T L T K N C K H F D
Rat Rattus norvegicus P84076 193 22409 L13 S K L R P E M L Q D L R E N T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520613 219 24982 S25 Q K L A E S L S K G L K H F T
Chicken Gallus gallus P42324 193 22251 L13 S K L R P E V L Q D L R E N T
Frog Xenopus laevis Q3KQ77 208 24147 S14 Q K Q A E A L S R L I K H F S
Zebra Danio Brachydanio rerio Q6AXL4 192 21965 Q14 K L R P E V I Q D L L D N T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P42325 190 21875 L13 S K L K P E V L E D L K Q N T
Honey Bee Apis mellifera XP_394805 307 34765 V23 E R G S G V S V D V G V G A D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25296 175 19620 L13 S K I V D G L L E D T N F D R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98 70.8 N.A. 91.5 24.6 N.A. 66.6 23.2 68.2 24.6 N.A. 21.3 34.8 N.A. N.A.
Protein Similarity: 100 100 98.5 74.9 N.A. 94.8 46.9 N.A. 79.4 44.5 79.1 45.5 N.A. 42.6 48.5 N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 13.3 N.A. 53.3 13.3 40 0 N.A. 20 0 N.A. N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 100 40 N.A. 73.3 40 66.6 33.3 N.A. 40 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 8 0 8 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 39 0 0 0 0 % C
% Asp: 0 0 0 0 47 0 0 0 16 31 0 8 0 8 24 % D
% Glu: 8 0 0 0 24 24 0 0 16 0 0 0 16 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 54 0 % F
% Gly: 0 0 8 0 8 8 0 0 0 8 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 % H
% Ile: 0 0 8 0 0 0 8 0 0 0 8 0 0 0 0 % I
% Lys: 8 85 0 8 0 0 0 0 47 0 0 62 0 0 0 % K
% Leu: 0 8 70 0 0 0 62 31 0 16 39 0 0 0 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 39 0 8 16 24 31 % N
% Pro: 0 0 0 8 24 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 54 0 8 0 0 0 0 8 16 0 0 0 8 0 0 % Q
% Arg: 0 8 8 16 0 0 0 0 8 0 0 16 0 0 8 % R
% Ser: 31 0 0 8 0 8 8 16 0 0 0 0 0 0 8 % S
% Thr: 0 0 0 39 0 39 0 31 0 0 8 0 0 8 31 % T
% Val: 0 0 0 8 0 16 16 8 0 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _