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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB1
All Species:
21.52
Human Site:
Y170
Identified Species:
39.44
UniProt:
Q9HAE3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAE3
NP_078869.1
211
24488
Y170
G
K
L
S
F
A
D
Y
E
L
A
V
R
E
E
Chimpanzee
Pan troglodytes
XP_528130
211
24456
Y170
G
K
L
S
F
A
D
Y
E
L
A
V
R
E
D
Rhesus Macaque
Macaca mulatta
XP_001101162
211
24440
Y170
G
K
L
S
F
A
D
Y
E
L
A
V
R
E
E
Dog
Lupus familis
XP_535064
271
31102
Y230
G
K
L
S
F
T
D
Y
E
Q
A
V
R
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3N2
212
24588
Y171
G
K
L
S
F
V
D
Y
E
K
A
V
R
E
E
Rat
Rattus norvegicus
P84076
193
22409
N160
F
R
Q
M
D
T
N
N
D
G
K
L
S
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520613
219
24982
F181
G
K
L
S
F
A
D
F
D
Q
A
V
R
E
E
Chicken
Gallus gallus
P42324
193
22251
N160
F
R
Q
M
D
T
N
N
D
G
K
L
S
L
E
Frog
Xenopus laevis
Q3KQ77
208
24147
F170
S
K
L
S
Y
T
D
F
E
K
A
V
Q
E
E
Zebra Danio
Brachydanio rerio
Q6AXL4
192
21965
R160
F
R
Q
M
D
T
N
R
D
G
K
L
S
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P42325
190
21875
P145
M
P
E
D
E
S
T
P
E
K
R
T
D
K
I
Honey Bee
Apis mellifera
XP_394805
307
34765
Y274
G
K
I
S
F
Q
D
Y
K
L
G
V
T
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25296
175
19620
T139
L
Q
Q
I
V
D
R
T
I
V
E
N
D
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98
70.8
N.A.
91.5
24.6
N.A.
66.6
23.2
68.2
24.6
N.A.
21.3
34.8
N.A.
N.A.
Protein Similarity:
100
100
98.5
74.9
N.A.
94.8
46.9
N.A.
79.4
44.5
79.1
45.5
N.A.
42.6
48.5
N.A.
N.A.
P-Site Identity:
100
93.3
100
86.6
N.A.
86.6
6.6
N.A.
80
6.6
60
6.6
N.A.
6.6
66.6
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
33.3
N.A.
93.3
33.3
80
33.3
N.A.
20
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
31
0
0
0
0
54
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
24
8
62
0
31
0
0
0
16
0
16
% D
% Glu:
0
0
8
0
8
0
0
0
54
0
8
0
0
62
77
% E
% Phe:
24
0
0
0
54
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
54
0
0
0
0
0
0
0
0
24
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
0
62
0
0
0
0
0
0
8
24
24
0
0
8
0
% K
% Leu:
8
0
54
0
0
0
0
0
0
31
0
24
0
24
0
% L
% Met:
8
0
0
24
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
24
16
0
0
0
8
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
8
31
0
0
8
0
0
0
16
0
0
8
0
0
% Q
% Arg:
0
24
0
0
0
0
8
8
0
0
8
0
47
0
0
% R
% Ser:
8
0
0
62
0
8
0
0
0
0
0
0
24
8
0
% S
% Thr:
0
0
0
0
0
39
8
8
0
0
0
8
8
0
0
% T
% Val:
0
0
0
0
8
8
0
0
0
8
0
62
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _