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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEAF6
All Species:
33.94
Human Site:
S122
Identified Species:
62.22
UniProt:
Q9HAF1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAF1
NP_073593.2
191
21635
S122
E
P
G
S
G
T
E
S
D
T
S
P
D
F
H
Chimpanzee
Pan troglodytes
XP_001169147
192
21690
S122
E
P
G
S
G
T
E
S
D
T
S
P
D
F
H
Rhesus Macaque
Macaca mulatta
XP_001111658
191
21616
S122
E
P
G
S
G
T
E
S
D
T
S
P
D
F
H
Dog
Lupus familis
XP_532558
190
21377
S111
E
P
G
S
G
T
E
S
D
T
S
P
D
F
H
Cat
Felis silvestris
Mouse
Mus musculus
Q2VPQ9
191
21630
S122
E
P
G
S
G
T
E
S
D
T
S
P
D
F
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511616
252
27933
S122
E
P
G
S
G
T
E
S
D
T
S
P
D
F
H
Chicken
Gallus gallus
Q5ZIX3
182
20440
E123
R
E
P
G
S
G
T
E
S
D
T
S
P
D
F
Frog
Xenopus laevis
Q52KD8
188
21154
S122
E
P
G
S
G
T
E
S
D
N
S
P
D
F
Q
Zebra Danio
Brachydanio rerio
Q6AZD3
192
21820
S122
E
P
G
S
G
T
E
S
D
T
S
P
D
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647981
225
24381
T154
T
T
A
H
D
G
T
T
T
I
K
S
T
P
K
Honey Bee
Apis mellifera
XP_001120359
100
11470
Y41
I
Y
A
F
E
G
S
Y
L
E
D
T
Q
L
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789981
185
20958
S123
Q
E
G
P
V
T
K
S
D
K
D
S
V
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SDW6
179
19021
S119
S
H
A
P
T
P
V
S
T
S
F
N
N
K
D
Conservation
Percent
Protein Identity:
100
92.7
100
85.8
N.A.
98.9
N.A.
N.A.
74.2
90.5
88.4
85.9
N.A.
40.4
39.7
N.A.
49.2
Protein Similarity:
100
94.7
100
86.9
N.A.
99.4
N.A.
N.A.
74.5
92.1
91.6
90.6
N.A.
53.3
46.5
N.A.
64.4
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
0
86.6
86.6
N.A.
0
0
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
6.6
86.6
86.6
N.A.
6.6
6.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
70
8
16
0
62
16
8
% D
% Glu:
62
16
0
0
8
0
62
8
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
0
54
8
% F
% Gly:
0
0
70
8
62
24
0
0
0
0
0
0
0
0
8
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
47
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
8
8
0
0
8
8
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
0
0
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
8
8
0
0
% N
% Pro:
0
62
8
16
0
8
0
0
0
0
0
62
8
8
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
16
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
62
8
0
8
77
8
8
62
24
0
0
0
% S
% Thr:
8
8
0
0
8
70
16
8
16
54
8
8
8
0
0
% T
% Val:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _