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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEAF6
All Species:
28.79
Human Site:
S136
Identified Species:
52.78
UniProt:
Q9HAF1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAF1
NP_073593.2
191
21635
S136
H
N
Q
E
N
E
P
S
Q
E
D
P
E
D
L
Chimpanzee
Pan troglodytes
XP_001169147
192
21690
S136
H
N
Q
E
N
E
P
S
Q
E
D
P
E
D
L
Rhesus Macaque
Macaca mulatta
XP_001111658
191
21616
S136
H
N
Q
E
N
E
P
S
Q
E
D
P
E
D
L
Dog
Lupus familis
XP_532558
190
21377
S125
H
N
Q
E
N
E
P
S
Q
E
D
P
E
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q2VPQ9
191
21630
A136
H
N
Q
E
N
E
P
A
Q
E
D
P
E
D
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511616
252
27933
S136
H
N
Q
E
N
E
P
S
Q
E
D
A
E
D
L
Chicken
Gallus gallus
Q5ZIX3
182
20440
P137
F
H
N
Q
E
N
E
P
S
Q
E
D
A
E
E
Frog
Xenopus laevis
Q52KD8
188
21154
S136
Q
N
Q
E
N
E
P
S
Q
D
D
T
E
D
L
Zebra Danio
Brachydanio rerio
Q6AZD3
192
21820
S136
Q
N
Q
E
N
E
P
S
Q
E
D
T
E
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647981
225
24381
S168
K
D
E
K
D
S
P
S
H
R
N
E
G
S
V
Honey Bee
Apis mellifera
XP_001120359
100
11470
W55
Y
G
N
I
I
R
G
W
D
R
Y
L
A
S
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789981
185
20958
V137
G
G
V
S
S
E
T
V
T
D
M
K
E
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SDW6
179
19021
T133
D
G
A
S
S
A
P
T
P
T
S
A
T
A
G
Conservation
Percent
Protein Identity:
100
92.7
100
85.8
N.A.
98.9
N.A.
N.A.
74.2
90.5
88.4
85.9
N.A.
40.4
39.7
N.A.
49.2
Protein Similarity:
100
94.7
100
86.9
N.A.
99.4
N.A.
N.A.
74.5
92.1
91.6
90.6
N.A.
53.3
46.5
N.A.
64.4
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
93.3
0
80
73.3
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
93.3
33.3
86.6
80
N.A.
53.3
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
41.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
8
0
0
0
16
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
0
0
0
8
16
62
8
0
54
0
% D
% Glu:
0
0
8
62
8
70
8
0
0
54
8
8
70
16
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
24
0
0
0
0
8
0
0
0
0
0
8
0
8
% G
% His:
47
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
54
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
62
16
0
62
8
0
0
0
0
8
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
77
8
8
0
0
39
0
0
8
% P
% Gln:
16
0
62
8
0
0
0
0
62
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
16
0
0
0
8
0
% R
% Ser:
0
0
0
16
16
8
0
62
8
0
8
0
0
16
0
% S
% Thr:
0
0
0
0
0
0
8
8
8
8
0
16
8
0
0
% T
% Val:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _