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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEAF6 All Species: 27.27
Human Site: S146 Identified Species: 50
UniProt: Q9HAF1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAF1 NP_073593.2 191 21635 S146 D P E D L D G S V Q G V K P Q
Chimpanzee Pan troglodytes XP_001169147 192 21690 S146 D P E D L D G S V Q G V K P Q
Rhesus Macaque Macaca mulatta XP_001111658 191 21616 S146 D P E D L D G S V Q G V K P Q
Dog Lupus familis XP_532558 190 21377 S135 D P E D L D G S V Q G V K P Q
Cat Felis silvestris
Mouse Mus musculus Q2VPQ9 191 21630 S146 D P E D L D G S V Q G V K P Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511616 252 27933 S146 D A E D L D A S V Q G V K P Q
Chicken Gallus gallus Q5ZIX3 182 20440 G147 E D A E E L D G S V Q G V K P
Frog Xenopus laevis Q52KD8 188 21154 S146 D T E D L D G S L S G V K P Q
Zebra Danio Brachydanio rerio Q6AZD3 192 21820 A146 D T E E A D G A L Q D L K P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647981 225 24381 G178 N E G S V V S G M V S G S T N
Honey Bee Apis mellifera XP_001120359 100 11470 A65 Y L A S N K N A N S K A D K R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789981 185 20958 S147 M K E R P M N S N R S G K I H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SDW6 179 19021 N143 S A T A G K A N S K K K K A A
Conservation
Percent
Protein Identity: 100 92.7 100 85.8 N.A. 98.9 N.A. N.A. 74.2 90.5 88.4 85.9 N.A. 40.4 39.7 N.A. 49.2
Protein Similarity: 100 94.7 100 86.9 N.A. 99.4 N.A. N.A. 74.5 92.1 91.6 90.6 N.A. 53.3 46.5 N.A. 64.4
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 86.6 0 80 53.3 N.A. 0 0 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 86.6 13.3 86.6 80 N.A. 20 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 29.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 41.8
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 16 8 8 0 16 16 0 0 0 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 62 8 0 54 0 62 8 0 0 0 8 0 8 0 0 % D
% Glu: 8 8 70 16 8 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 8 0 54 16 0 0 54 24 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 8 0 0 0 16 0 0 0 8 16 8 77 16 0 % K
% Leu: 0 8 0 0 54 8 0 0 16 0 0 8 0 0 0 % L
% Met: 8 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 16 8 16 0 0 0 0 0 8 % N
% Pro: 0 39 0 0 8 0 0 0 0 0 0 0 0 62 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 54 8 0 0 0 62 % Q
% Arg: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 8 % R
% Ser: 8 0 0 16 0 0 8 62 16 16 16 0 8 0 0 % S
% Thr: 0 16 8 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 8 8 0 0 47 16 0 54 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _