Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEAF6 All Species: 33.94
Human Site: S167 Identified Species: 62.22
UniProt: Q9HAF1 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAF1 NP_073593.2 191 21635 S167 S S G S H H S S H K K R K N K
Chimpanzee Pan troglodytes XP_001169147 192 21690 S167 S S G S H H S S H K K R K N K
Rhesus Macaque Macaca mulatta XP_001111658 191 21616 S167 S S G S H H S S H K K R K N K
Dog Lupus familis XP_532558 190 21377 S156 S S G S H H S S H K K R K N K
Cat Felis silvestris
Mouse Mus musculus Q2VPQ9 191 21630 S167 S S G S H H S S H K K R K N K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511616 252 27933 S167 S S G S H H S S H K K R K N K
Chicken Gallus gallus Q5ZIX3 182 20440 S168 T S G S H H S S H K K R K N K
Frog Xenopus laevis Q52KD8 188 21154 S167 N S G G H H S S H K K R K N K
Zebra Danio Brachydanio rerio Q6AZD3 192 21820 H167 S G S H H S S H K K R K N K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647981 225 24381 N199 L L G T P T S N T K S K L S T
Honey Bee Apis mellifera XP_001120359 100 11470 S86 A E R L F S K S S I T S M A V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789981 185 20958 R168 K K R K N K S R H R L E G R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SDW6 179 19021 S164 V E D S E T D S R E T K K A R
Conservation
Percent
Protein Identity: 100 92.7 100 85.8 N.A. 98.9 N.A. N.A. 74.2 90.5 88.4 85.9 N.A. 40.4 39.7 N.A. 49.2
Protein Similarity: 100 94.7 100 86.9 N.A. 99.4 N.A. N.A. 74.5 92.1 91.6 90.6 N.A. 53.3 46.5 N.A. 64.4
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 100 93.3 86.6 26.6 N.A. 20 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 100 100 93.3 40 N.A. 46.6 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 29.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 41.8
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 16 0 0 8 0 0 0 0 8 0 8 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 70 8 0 0 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 8 70 62 0 8 70 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % I
% Lys: 8 8 0 8 0 8 8 0 8 77 62 24 70 8 62 % K
% Leu: 8 8 0 8 0 0 0 0 0 0 8 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 8 0 0 8 0 0 0 0 8 62 8 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 16 0 0 0 0 8 8 8 8 62 0 8 8 % R
% Ser: 54 62 8 62 0 16 85 77 8 0 8 8 0 8 0 % S
% Thr: 8 0 0 8 0 16 0 0 8 0 16 0 0 0 8 % T
% Val: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _