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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NMNAT1 All Species: 6.97
Human Site: S140 Identified Species: 11.79
UniProt: Q9HAN9 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAN9 NP_073624.2 279 31932 S140 Q D S S Q K K S L E P K T K A
Chimpanzee Pan troglodytes XP_001168527 254 29013 K119 Q K K S L E P K T K A V P K V
Rhesus Macaque Macaca mulatta XP_001118727 179 20456 K44 Q K K S L E P K T K A V P K V
Dog Lupus familis XP_536739 279 31883 S140 Q D F S Q K K S L E P K T K D
Cat Felis silvestris
Mouse Mus musculus Q9EPA7 285 32337 K140 K Q D S S P Q K P Q E P K P T
Rat Rattus norvegicus Q0HA29 307 34426 N140 N T Q P I Y Q N S N V P T K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507826 272 31049 L137 L L C G A D L L E S F G I P N
Chicken Gallus gallus XP_417605 284 32371 K143 N R H D P I K K K N Q S P D G
Frog Xenopus laevis NP_001091188 278 32072 L141 Q D K P N S Y L Q E N K A V P
Zebra Danio Brachydanio rerio Q6PC93 304 34191 T140 T S A I Y Q N T V N K S V A I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651315 389 43777 G153 H I N S G G G G G D D G E N T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91851 223 25149 T88 E C T R T T W T R T I D V L R
Sea Urchin Strong. purpuratus XP_783084 287 32645 T151 E P P A S N D T E V D D A Y G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53204 395 44891 K151 P V H R L T K K L Q D P E K L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 62 86.3 N.A. 80.6 28.6 N.A. 63.7 69.7 60.9 26.9 N.A. 33.9 N.A. 26.1 47.3
Protein Similarity: 100 89.6 62.3 92.1 N.A. 89.4 48.5 N.A. 76.3 82 76.3 46.7 N.A. 48 N.A. 44 67.9
P-Site Identity: 100 20 20 86.6 N.A. 6.6 13.3 N.A. 0 6.6 26.6 0 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 33.3 33.3 86.6 N.A. 26.6 26.6 N.A. 0 6.6 26.6 26.6 N.A. 20 N.A. 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 8 0 0 0 0 0 15 0 15 8 8 % A
% Cys: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 22 8 8 0 8 8 0 0 8 22 15 0 8 8 % D
% Glu: 15 0 0 0 0 15 0 0 15 22 8 0 15 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 0 8 8 8 8 8 8 0 0 15 0 0 15 % G
% His: 8 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 8 8 0 0 0 0 8 0 8 0 8 % I
% Lys: 8 15 22 0 0 15 29 36 8 15 8 22 8 43 0 % K
% Leu: 8 8 0 0 22 0 8 15 22 0 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 8 0 8 8 8 8 0 22 8 0 0 8 8 % N
% Pro: 8 8 8 15 8 8 15 0 8 0 15 22 22 15 15 % P
% Gln: 36 8 8 0 15 8 15 0 8 15 8 0 0 0 0 % Q
% Arg: 0 8 0 15 0 0 0 0 8 0 0 0 0 0 8 % R
% Ser: 0 8 8 43 15 8 0 15 8 8 0 15 0 0 0 % S
% Thr: 8 8 8 0 8 15 0 22 15 8 0 0 22 0 15 % T
% Val: 0 8 0 0 0 0 0 0 8 8 8 15 15 8 15 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 8 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _