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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NMNAT1 All Species: 20.61
Human Site: Y55 Identified Species: 34.87
UniProt: Q9HAN9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAN9 NP_073624.2 279 31932 Y55 I S P V G D A Y K K K G L I P
Chimpanzee Pan troglodytes XP_001168527 254 29013 G34 G D A Y K K K G L I P A Y H R
Rhesus Macaque Macaca mulatta XP_001118727 179 20456
Dog Lupus familis XP_536739 279 31883 K55 S P V G D A Y K K K G L I S A
Cat Felis silvestris
Mouse Mus musculus Q9EPA7 285 32337 Y55 I S P V G D A Y K K K G L I P
Rat Rattus norvegicus Q0HA29 307 34426 Y55 V S P V H D S Y G K Q G L V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507826 272 31049 S52 I K L A T Q T S K W V E V D D
Chicken Gallus gallus XP_417605 284 32371 Y58 I S P V G D A Y K K K G L I S
Frog Xenopus laevis NP_001091188 278 32072 Y56 I S P V C D G Y K K K G L I E
Zebra Danio Brachydanio rerio Q6PC93 304 34191 Y55 V S P V H D S Y G K P G L V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651315 389 43777 A68 H L R M F E I A K D H F E M Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91851 223 25149
Sea Urchin Strong. purpuratus XP_783084 287 32645 E66 I S S K H R I E M C K M A V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53204 395 44891 N66 S S R K K N A N S S N R M D H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.1 62 86.3 N.A. 80.6 28.6 N.A. 63.7 69.7 60.9 26.9 N.A. 33.9 N.A. 26.1 47.3
Protein Similarity: 100 89.6 62.3 92.1 N.A. 89.4 48.5 N.A. 76.3 82 76.3 46.7 N.A. 48 N.A. 44 67.9
P-Site Identity: 100 0 0 13.3 N.A. 100 53.3 N.A. 13.3 93.3 80 60 N.A. 6.6 N.A. 0 20
P-Site Similarity: 100 0 0 20 N.A. 100 80 N.A. 20 93.3 80 80 N.A. 26.6 N.A. 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 29 8 0 0 0 8 8 0 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 8 0 0 8 43 0 0 0 8 0 0 0 15 8 % D
% Glu: 0 0 0 0 0 8 0 8 0 0 0 8 8 0 15 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 8 0 0 8 22 0 8 8 15 0 8 43 0 0 0 % G
% His: 8 0 0 0 22 0 0 0 0 0 8 0 0 8 8 % H
% Ile: 43 0 0 0 0 0 15 0 0 8 0 0 8 29 0 % I
% Lys: 0 8 0 15 15 8 8 8 50 50 36 0 0 0 0 % K
% Leu: 0 8 8 0 0 0 0 0 8 0 0 8 43 0 0 % L
% Met: 0 0 0 8 0 0 0 0 8 0 0 8 8 8 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 8 0 0 0 0 % N
% Pro: 0 8 43 0 0 0 0 0 0 0 15 0 0 0 22 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 8 % Q
% Arg: 0 0 15 0 0 8 0 0 0 0 0 8 0 0 8 % R
% Ser: 15 58 8 0 0 0 15 8 8 8 0 0 0 8 15 % S
% Thr: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % T
% Val: 15 0 8 43 0 0 0 0 0 0 8 0 8 22 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 8 43 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _