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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIP
All Species:
13.33
Human Site:
S345
Identified Species:
29.33
UniProt:
Q9HAP2
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAP2
NP_055753.3
919
101185
S345
S
S
R
S
I
F
G
S
M
L
P
A
S
A
S
Chimpanzee
Pan troglodytes
XP_509441
819
90122
P274
I
L
P
T
T
A
L
P
T
V
S
L
P
D
S
Rhesus Macaque
Macaca mulatta
XP_001094210
822
90630
P277
V
L
Q
T
T
A
L
P
T
V
S
L
P
D
S
Dog
Lupus familis
XP_859822
916
100303
S345
S
S
R
S
I
F
G
S
M
L
P
A
P
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q2VPU4
917
100785
S345
S
S
R
S
I
F
G
S
M
L
P
P
P
S
S
Rat
Rattus norvegicus
XP_001079320
917
100573
S345
S
S
R
S
I
F
G
S
M
L
P
P
P
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415149
682
74550
T137
K
R
R
Y
G
R
E
T
P
V
P
M
E
E
G
Frog
Xenopus laevis
NP_001084764
548
60887
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
A272
N
P
R
E
I
A
H
A
G
N
A
D
M
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394429
1014
115124
Y375
L
Q
Y
T
A
K
I
Y
T
Q
P
Q
P
E
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
Q575
A
A
R
S
S
K
L
Q
T
V
T
P
I
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
84.8
89.6
N.A.
87
85
N.A.
N.A.
49.7
37.6
52.2
N.A.
N.A.
27.1
N.A.
23.9
Protein Similarity:
100
87.2
86.8
92.3
N.A.
90.3
88.7
N.A.
N.A.
55.9
46.3
62.5
N.A.
N.A.
43.9
N.A.
36.8
P-Site Identity:
100
6.6
6.6
86.6
N.A.
80
80
N.A.
N.A.
13.3
0
13.3
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
20
26.6
86.6
N.A.
86.6
80
N.A.
N.A.
26.6
0
26.6
N.A.
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
10
28
0
10
0
0
10
19
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
19
0
% D
% Glu:
0
0
0
10
0
0
10
0
0
0
0
0
10
19
0
% E
% Phe:
0
0
0
0
0
37
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
37
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
46
0
10
0
0
0
0
0
10
10
0
% I
% Lys:
10
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
19
0
0
0
0
28
0
0
37
0
19
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
37
0
0
10
10
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
19
10
0
55
28
55
0
10
% P
% Gln:
0
10
10
0
0
0
0
10
0
10
0
10
0
0
10
% Q
% Arg:
0
10
64
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
37
37
0
46
10
0
0
37
0
0
19
0
10
10
55
% S
% Thr:
0
0
0
28
19
0
0
10
37
0
10
0
0
19
0
% T
% Val:
10
0
0
0
0
0
0
0
0
37
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _