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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLXIP All Species: 5.45
Human Site: S639 Identified Species: 12
UniProt: Q9HAP2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAP2 NP_055753.3 919 101185 S639 T D L G H G T S S P P A P V S
Chimpanzee Pan troglodytes XP_509441 819 90122 G558 S T A Q D P L G K G E Q V P L
Rhesus Macaque Macaca mulatta XP_001094210 822 90630 G561 S T A Q D P L G K G E Q V Q L
Dog Lupus familis XP_859822 916 100303 S643 T D L G H T T S S Q P A P V S
Cat Felis silvestris
Mouse Mus musculus Q2VPU4 917 100785 P639 S H S T S S Q P S P V S R L F
Rat Rattus norvegicus XP_001079320 917 100573 P639 S H S T S S Q P S P A S R L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415149 682 74550 L421 Q S Q L T F A L P K A V P L A
Frog Xenopus laevis NP_001084764 548 60887 D287 F P L Q P N L D L M D T F E S
Zebra Danio Brachydanio rerio XP_001338503 817 90800 P556 S A G F H I L P Q T Q K S P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394429 1014 115124 A703 S S M L P P S A S P T Q I T T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788672 1338 148936 T980 A K S E I G K T S T S S S S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 84.8 89.6 N.A. 87 85 N.A. N.A. 49.7 37.6 52.2 N.A. N.A. 27.1 N.A. 23.9
Protein Similarity: 100 87.2 86.8 92.3 N.A. 90.3 88.7 N.A. N.A. 55.9 46.3 62.5 N.A. N.A. 43.9 N.A. 36.8
P-Site Identity: 100 0 0 86.6 N.A. 13.3 13.3 N.A. N.A. 6.6 13.3 6.6 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 6.6 6.6 86.6 N.A. 33.3 33.3 N.A. N.A. 20 13.3 13.3 N.A. N.A. 46.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 19 0 0 0 10 10 0 0 19 19 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 0 19 0 0 10 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 19 0 0 10 0 % E
% Phe: 10 0 0 10 0 10 0 0 0 0 0 0 10 0 19 % F
% Gly: 0 0 10 19 0 19 0 19 0 19 0 0 0 0 0 % G
% His: 0 19 0 0 28 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 10 0 0 0 0 10 0 19 10 0 10 0 0 0 % K
% Leu: 0 0 28 19 0 0 37 10 10 0 0 0 0 28 19 % L
% Met: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 19 28 0 28 10 37 19 0 28 19 0 % P
% Gln: 10 0 10 28 0 0 19 0 10 10 10 28 0 10 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % R
% Ser: 55 19 28 0 19 19 10 19 55 0 10 28 19 10 28 % S
% Thr: 19 19 0 19 10 10 19 10 0 19 10 10 0 10 19 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 10 19 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _