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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLXIP All Species: 13.64
Human Site: S86 Identified Species: 30
UniProt: Q9HAP2 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAP2 NP_055753.3 919 101185 S86 S G H F M V S S P H R E H P P
Chimpanzee Pan troglodytes XP_509441 819 90122 K50 S P K W K N F K G L K L Q W R
Rhesus Macaque Macaca mulatta XP_001094210 822 90630 K53 S P K W K N F K G L K L Q W R
Dog Lupus familis XP_859822 916 100303 S86 S G H F M V S S P H R E H P P
Cat Felis silvestris
Mouse Mus musculus Q2VPU4 917 100785 S86 S G H F M V S S P H R E H P P
Rat Rattus norvegicus XP_001079320 917 100573 S86 S G H F M V S S P H R E H P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415149 682 74550
Frog Xenopus laevis NP_001084764 548 60887
Zebra Danio Brachydanio rerio XP_001338503 817 90800 V48 I H S G H F M V S S P H T D H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394429 1014 115124 A77 E E E A V K V A I I T P P G L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788672 1338 148936 G211 K K K L S H A G L L E E G S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 84.8 89.6 N.A. 87 85 N.A. N.A. 49.7 37.6 52.2 N.A. N.A. 27.1 N.A. 23.9
Protein Similarity: 100 87.2 86.8 92.3 N.A. 90.3 88.7 N.A. N.A. 55.9 46.3 62.5 N.A. N.A. 43.9 N.A. 36.8
P-Site Identity: 100 6.6 6.6 100 N.A. 100 100 N.A. N.A. 0 0 0 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 20 20 100 N.A. 100 100 N.A. N.A. 0 0 0 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 10 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 10 10 10 0 0 0 0 0 0 0 10 46 0 0 0 % E
% Phe: 0 0 0 37 0 10 19 0 0 0 0 0 0 0 0 % F
% Gly: 0 37 0 10 0 0 0 10 19 0 0 0 10 10 0 % G
% His: 0 10 37 0 10 10 0 0 0 37 0 10 37 0 10 % H
% Ile: 10 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % I
% Lys: 10 10 28 0 19 10 0 19 0 0 19 0 0 0 0 % K
% Leu: 0 0 0 10 0 0 0 0 10 28 0 19 0 0 19 % L
% Met: 0 0 0 0 37 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 19 0 0 0 0 0 0 37 0 10 10 10 37 37 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 37 0 0 0 19 % R
% Ser: 55 0 10 0 10 0 37 37 10 10 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % T
% Val: 0 0 0 0 10 37 10 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 19 0 0 0 0 0 0 0 0 0 19 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _