KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIP
All Species:
13.94
Human Site:
T274
Identified Species:
30.67
UniProt:
Q9HAP2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAP2
NP_055753.3
919
101185
T274
E
E
D
P
L
L
D
T
D
M
L
M
S
E
F
Chimpanzee
Pan troglodytes
XP_509441
819
90122
F225
P
L
Q
P
N
L
D
F
M
D
T
F
E
P
F
Rhesus Macaque
Macaca mulatta
XP_001094210
822
90630
F228
P
L
Q
P
N
L
D
F
M
D
T
F
E
P
F
Dog
Lupus familis
XP_859822
916
100303
T274
E
E
D
P
L
L
D
T
D
M
L
M
S
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q2VPU4
917
100785
T274
E
E
D
S
L
L
D
T
D
M
L
M
S
E
F
Rat
Rattus norvegicus
XP_001079320
917
100573
T274
E
E
D
S
L
L
D
T
D
M
L
M
S
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415149
682
74550
R88
T
E
G
K
Y
W
K
R
R
I
E
I
V
I
R
Frog
Xenopus laevis
NP_001084764
548
60887
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
R223
A
G
G
R
R
R
S
R
R
S
R
D
S
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394429
1014
115124
T252
M
T
D
T
L
F
S
T
I
S
S
N
Q
P
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
Q425
F
N
L
A
G
M
Q
Q
Q
V
Q
V
G
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
84.8
89.6
N.A.
87
85
N.A.
N.A.
49.7
37.6
52.2
N.A.
N.A.
27.1
N.A.
23.9
Protein Similarity:
100
87.2
86.8
92.3
N.A.
90.3
88.7
N.A.
N.A.
55.9
46.3
62.5
N.A.
N.A.
43.9
N.A.
36.8
P-Site Identity:
100
26.6
26.6
100
N.A.
93.3
93.3
N.A.
N.A.
6.6
0
6.6
N.A.
N.A.
20
N.A.
0
P-Site Similarity:
100
26.6
26.6
100
N.A.
93.3
93.3
N.A.
N.A.
20
0
6.6
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
46
0
0
0
55
0
37
19
0
10
0
10
0
% D
% Glu:
37
46
0
0
0
0
0
0
0
0
10
0
19
37
0
% E
% Phe:
10
0
0
0
0
10
0
19
0
0
0
19
0
0
55
% F
% Gly:
0
10
19
0
10
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
0
10
0
10
10
% I
% Lys:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
19
10
0
46
55
0
0
0
0
37
0
0
0
10
% L
% Met:
10
0
0
0
0
10
0
0
19
37
0
37
0
0
0
% M
% Asn:
0
10
0
0
19
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
19
0
0
37
0
0
0
0
0
0
0
0
0
37
0
% P
% Gln:
0
0
19
0
0
0
10
10
10
0
10
0
10
0
0
% Q
% Arg:
0
0
0
10
10
10
0
19
19
0
10
0
0
0
10
% R
% Ser:
0
0
0
19
0
0
19
0
0
19
10
0
46
0
0
% S
% Thr:
10
10
0
10
0
0
0
46
0
0
19
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
10
10
0
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _