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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIP
All Species:
7.88
Human Site:
T405
Identified Species:
17.33
UniProt:
Q9HAP2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAP2
NP_055753.3
919
101185
T405
G
C
E
H
T
S
R
T
E
D
P
F
I
Q
P
Chimpanzee
Pan troglodytes
XP_509441
819
90122
M334
P
F
L
P
V
F
T
M
P
L
L
S
P
S
P
Rhesus Macaque
Macaca mulatta
XP_001094210
822
90630
M337
P
F
L
P
V
F
T
M
P
L
L
S
P
S
P
Dog
Lupus familis
XP_859822
916
100303
P405
G
C
E
R
A
P
R
P
G
D
P
F
I
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q2VPU4
917
100785
T405
G
C
E
R
T
S
Q
T
V
D
P
F
I
Q
P
Rat
Rattus norvegicus
XP_001079320
917
100573
S405
G
C
E
R
T
S
Q
S
V
D
P
F
I
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415149
682
74550
N197
G
L
I
P
L
Q
P
N
F
D
F
M
D
T
F
Frog
Xenopus laevis
NP_001084764
548
60887
G63
S
E
H
P
P
K
K
G
Y
D
F
D
T
V
N
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
A332
S
S
S
S
Q
T
Q
A
S
L
L
S
S
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394429
1014
115124
R435
V
I
Q
Q
S
Q
Q
R
N
T
Y
Q
R
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
L635
G
S
Q
N
G
S
M
L
Q
G
G
N
T
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
84.8
89.6
N.A.
87
85
N.A.
N.A.
49.7
37.6
52.2
N.A.
N.A.
27.1
N.A.
23.9
Protein Similarity:
100
87.2
86.8
92.3
N.A.
90.3
88.7
N.A.
N.A.
55.9
46.3
62.5
N.A.
N.A.
43.9
N.A.
36.8
P-Site Identity:
100
6.6
6.6
66.6
N.A.
80
73.3
N.A.
N.A.
13.3
6.6
6.6
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
6.6
6.6
66.6
N.A.
86.6
86.6
N.A.
N.A.
13.3
13.3
20
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
10
% A
% Cys:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
55
0
10
10
0
0
% D
% Glu:
0
10
37
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
19
0
0
0
19
0
0
10
0
19
37
0
0
10
% F
% Gly:
55
0
0
0
10
0
0
10
10
10
10
0
0
0
0
% G
% His:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
37
0
0
% I
% Lys:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
19
0
10
0
0
10
0
28
28
0
0
10
0
% L
% Met:
0
0
0
0
0
0
10
19
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
10
0
0
10
0
0
10
% N
% Pro:
19
0
0
37
10
10
10
10
19
0
37
0
19
0
64
% P
% Gln:
0
0
19
10
10
19
37
0
10
0
0
10
0
37
10
% Q
% Arg:
0
0
0
28
0
0
19
10
0
0
0
0
10
0
0
% R
% Ser:
19
19
10
10
10
37
0
10
10
0
0
28
10
19
0
% S
% Thr:
0
0
0
0
28
10
19
19
0
10
0
0
19
19
0
% T
% Val:
10
0
0
0
19
0
0
0
19
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _